A Review on the Role of Neuroplasticity in Neurodegenerative Disorders and Its Possible Pharmacological and Non-Pharmacological Interventions
Rana Muhammad Nabeel Aslam, Noor-ul-Ain, Husnain Ali, Ayesha Muzammil, Anam Iqbal
Asian Journal of Medicine and Health · pp. 72–86 · Published 31 Jan 2024
10.9734/ajmah/2024/v22i1977Abstract
Neuroplasticity is the capability of brain cells to interchange as well as modify for the ultimate cause of higher proficiency to acclimatize to the new situations. Neuroplasticity also plays a very pivotal role in the development and then further progressing of neurodegenerative disorders. The severe adjustments in neural plasticity caused by high pressure, anxiety and other terrible stimuli like stress play a considerable role in the onset and cause of depression. This comprehensive review explores the pivotal role of neuroplasticity in neurodegenerative disorders, shedding light on the dynamic adaptive processes of the nervous system in response to pathological conditions. The paper synthesizes current research findings to elucidate the intricate interplay between neuroplasticity and the progression of neurodegenerative diseases. Furthermore, it delves into potential pharmacological and non-pharmacological interventions aimed at modulating neuroplasticity to ameliorate or mitigate the impact of these disorders. By examining diverse strategies, from pharmaceutical interventions to lifestyle modifications, this review contributes to a nuanced understanding of the multifaceted mechanisms underlying neurodegeneration and offers insights into promising avenues for therapeutic development.
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