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Research Article Open access CC BY 4.0

A Retrospective Review of Blood Component Transfusions in Prehospital Aeromedical Care

Breno de Almeida MOURA, Mateus Caldeira BARBOSA, Heros Souza COUTO JUNIOR, Ana Carolina de Castro Bahia DARÉ, Rosana Aguiar COSSENZO, Camila de Aguiar LIMA

Journal of Advances in Medicine and Medical Research · pp. 1–8 · Published 4 Jun 2025

10.9734/jammr/2025/v37i65846

Abstract

Background: Early administration of blood products has become increasingly important in aeromedical transport due to its potential to improve outcomes in critically ill trauma patients by stabilizing hemodynamics and reducing mortality. This study aims to analyze current practices and future perspectives of blood component transfusion in prehospital aeromedical care. Study Design:  A descriptive, qualitative, and retrospective observational study, utilizing a methodological framework based on a bibliographic review of indexed journal articles. Methodology: A systematic search on PubMed was conducted using the terms “blood components,” “transfusion,” “aeromedical,” and “pre-hospital,” limited to the last 10 years. Thirty-four articles were selected and analyzed according to thematic relevance. Results: Prehospital blood transfusion (PHBT) has been documented as a safe procedure that optimizes care and facilitates effective hemodynamic management in trauma patients, as well as significantly reduces mortality rates and improves shock index stabilization. Studies highlight favorable outcomes associated with PHBT, emphasizing the need for its efficient integration, particularly in aeromedical services. Challenges specific to aeromedical transport include maintaining blood product temperature and viability during flight, managing limited onboard storage capacity, and coping with physiological stressors such as vibration and altitude changes that may affect transfusion safety and efficacy. Despite these challenges, PHBT enhances early hemodynamic management and facilitates timely hemorrhage control. Conclusion: Evidence supports that blood transfusion during prehospital aeromedical transport can improve patient survival and hemodynamic stability. Further research is essential to develop optimized protocols that address the unique logistical and physiological challenges of aeromedical environments to ensure patient safety and maximize clinical benefits.

Blood products hemostatic resuscitation trauma care massive transfusion

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