A Rare Site of Presentation of B Cell Lymphoblastic Lymphoma
Jaistri Jaishankar, K. Senthilkumar, R. Anantharamakrishnan, . Megha
Journal of Pharmaceutical Research International · pp. 127–131 · Published 29 Dec 2021
10.9734/jpri/2021/v33i63A35224Abstract
Lymphoblastic lymphoma is seen accounting to about 2% of all the lymphomas and it is a neoplasm of precursor B cells. Lymphoblastic lymphoma is highly aggressive, but is now frequently curable with recent therapy. Lymphoblastic lymphoma is associated with radiation exposure and also exposure to pesticide. The lymphoblasts infiltrate nodal or extranodal structures and is commonly associated with large mediastinal masses with a high chances for spreading to bone marrow and the central nervous system. The prognosis in all age groups has drastically improved with the use of intensive ALL-type chemotherapy regimes, with a disease-free survival of 73-90% in children and 45-72% in adults.
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