A Case Report on Libman-sacks Endocarditis Superinfected

Abstract

Libman-Sacks endocarditis is a rare cardiac manifestation systemic lupus erythematosus, in which there is a sterile vegetation in the heart valves. There is a significant risk of infective endocarditis. Our patient was a 63 year old woman with persistent fever with and generalized crusty, pruritic lesions. She was febrile at 38.9 °C, had a mitral systolic murmur 3/6 and aortic diastolic murmur 2/6. We have objectified an inflammatory syndrome, blood cultures were negative. The dosage of anti-nuclear antibody was positive with a mottled appearance, as well as anti-DNA antibodies. The Doppler echocardiography had objectified vegetations in the mitral, aortic and tricuspid valves. Clinical, biological and morphological improvements were obtained after antibiotic and corticosteroid combination. We can conclude that LibmanSacks endocarditis evolution is favorable in the absence of an associated antiphospholipid syndrome (APS). Always fear in all cases a superinfection. The treatment is based on the combination antibiotic-corticosteroid-synthetic antimalarial.