Faecal Carriage and Antibiotics Resistance Patterns of Campylobacter Species from HIV/AIDS Patients in Ibadan, Southwest Nigeria
Olutayo Israel Falodun, Emmanuel Adedapo Adesola, Ebenezer Adewuyi Ademola, Solomon A. Bakarey
South Asian Journal of Research in Microbiology · pp. 39–46 · Published 13 Oct 2020
10.9734/sajrm/2020/v7i430181Abstract
Background: As a result of the low immunosuppressive condition of people living with Human Immunodeficiency Virus and Acquired Immune Deficiency Syndrome (HIV/AIDS), they are at greater risk of Campylobacter infections but the use of antibiotics tends to reduce incidence. However, though this has reduced the incidence of the infection, there is likely development of antibiotic resistance with them thereby becoming asymptomatic carriers of drug resistant Campylobacter species. Aim: This study was carried out to determine the faecal carriage and antibiotic susceptibility pattern of Campylobacter species isolated from HIV patients in Ibadan, Nigeria. Methods: One Hundred stool samples were collected from HIV patients attending two Antiretroviral Clinics in Ibadan between February and March, 2017. Campylobacter species were isolated and identified using standard methods. Antibiotic susceptibility test of the isolates to amikacin, gentamycin, chloramphenicol, amoxicillin/clavulanate, cefixime, aztreonam, ciprofloxacin, cephalothin, nalidixic acid and ertapenem was done using disk diffusion method. Results: The prevalence of Campylobacter species in the stool samples of the HIV/AIDS patients was 68%. A total of one hundred and twenty isolates were identified as C. upsaliensis 32(26.7%), C. jejuni 30(25%), C. lari 23(19.2%), C. coli 20(16.7%), and C. fetus 15(12.5%). The antibiotics susceptibility pattern of these isolates showed that 97(80.8%), 88(73.3%), 82(68.3%), 9(7.5%), 9(7.5%) and 12 (10.8%) were resistant to gentamycin, chloramphenicol, cefixime, amikacin, ciprofloxacin and ertapenem respectively. Moreover, 102 (85.0%) of the isolates were found to be multidrug resistant. Conclusions: The faecal carriage and high prevalence of antibiotic resistance of Campylobacter strains among the HIV/AIDS patients therefore present them as asymptomatic carrier and reservoir for dissemination of the bacteria.
Cited by 4
4 citations reported by external sources — individual citing-article records aren't available to list yet.
Related research
- Urine Analysis and Determination of Drug Sensitivity Pattern of Isolated Escherichia coli from Urinary Tract Infected Patients — shares topic coverage
- Alternative Strategies in the Treatment of Clostridioides difficile Infection — shares topic coverage
- Community Acquired Pneumonia in Bangladesh: Sensitivity Pattern, Clinical Courses and Outcome of a Cross Sectional Population — shares topic coverage
- Knowledge and Perception of HealthCare Workers on Antibiotic Resistance and Predictors of Antibiotic Prescription in Benue State, Nigeria — shares topic coverage
- Genotypic Analysis of Klebsiella pneumoniae among Patients Admitted in Critical Care Settings in a Tertiary Care Center of Bangladesh — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
4
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.