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Research Article Open access CC BY 4.0

Phenyliodine(III)diacetate (PIDA): Applications in Organic Synthesis

Ravi Varala, Vittal Seema, Narsimhaswamy Dubasi

Organics · pp. 1–40 · Published 23 Dec 2022

10.3390/org4010001

Abstract

One of the hypervalent iodines most widely used as an oxidizing agent in organic chemistry is (diacetoxyiodo)benzene (PhI(OAc)2), also known as (DAIB), phenyliodine(III) diacetate (PIDA). In this septennial mini-review, the authors have concisely and systematically presented representative applications of PIDA in organic synthesis involving C-H functionalization, hetero-hetero bond formations, heterocyclic ring construction, rearrangements or migrations and miscellaneous reactions along with their interesting mechanistic aspects starting from the summer of 2015 to the present.

Hypervalent molecule Oxidizing agent Organic synthesis Chemistry Benzene Ring (chemistry) Combinatorial chemistry Organic chemistry

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