Effect of Apple Cider Vinegar (ACV) “With Mother” on Progesterone, Testosterone and Estrogen of Wistar Rats

Abstract

Aim: Apple cider vinegar (ACV) with mother" has been singled out as an especially helpful health remedy. This present research evaluated the effect of ACV ‘with mother’ on hormones (testosterone, estrogen and progesterone) of Wistar rats. Materials and Methods: Eighteen rats with average weight range of 120 g were grouped into six groups. Three groups served as the control for each week (week 1, 2 and 3) while the remaining three groups were treated with 1 ml of ACV twice daily. The animals were treated for a total of 21 days. After each week the animals in that group were sacrificed and laboratory analyses were performed. Results: After oral administration of the product, the results revealed significant reductions in a time dependent manner with the highest reductions obtained on the last week of experiment. The result obtained for estrogen showed significant reduction (p<0.05) in week one with test value (7.74±0.19 mlU/ml) as compared to control (8.36±0.01 mlU/ml).For progesterone, there was an increase (p<0.05). The highest test value was obtained in week 3, (3.64±0.08 mlU/ml) as compared to control value (3.15±0.01 mlU/ml). However, there was also a reduction in testosterone level. Conclusion: In conclusion, ACV reduces the levels of estrogen and testosterone but increased progesterone level of Wistar rats.