Biology of Pathogenicity (Theoretical Review)
Annual Research & Review in Biology · pp. 805–813 · Published 28 Jul 2013
Abstract
Phenomenon of pathogenicity is the polyfunctional biological potency of germs that are realized by factors (determinants) of pathogenicity [1]. Bacterial pathogenicity is an ability of bacteria to induce and develop infectious diseases in multi-cellular organisms (human, animals and plants). Virulence is a degree of pathogenicity measured by the in vivo (LD50) and in vitro (ID50) tests (highly virulent, weakly virulent and non-virulent strains). Pathogenic factors (determinants) are the bio-molecules produced by pathogen and are responsible for interaction with the host tissue cells. “Pathogenicity Islands” are the bacterial genome mobile elements that carry genes encoding the pathogenicity factors production.
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