Platelet Alteration in Plasmodium vivax Malaria Patients in Thailand
Mohammand Sami Hayat, Polrat Wilairatana, Noppadon Tangpukdee, Srivicha Krudsood, Nalinrat Wilairat, Pichayapat Wilairat, Pimjira Thebpatipat
Asian Journal of Medicine and Health · pp. 1–6 · Published 1 Aug 2019
10.9734/ajmah/2019/v15i330125Abstract
Introduction: Malaria remains a global health problem. Malaria is often linked to thrombocytopenia as well as other hematological variations. Objective: The aim of this study is to find the platelet changes in Plasmodium vivax malaria patients. This retrospective cross-sectional study included 204 malaria patients admitted to the Hospital for Tropical Diseases, Bangkok, Thailand. Results: Thrombocytopenia (<150x103/µl) was seen in 170(83.3%) patients with a mean (SD) of 101x103/µl (56.5). Mild (150x103/µl-50x103/µl), moderate (50x103/µl-20x103/µl) and severe (<20x103/µl) thrombocytopenia were seen in 141 (69.1%), 25 (12.2%) and 4 (2%) patients respectively. None of these patients with thrombocytopenia showed any sign of bleeding or required platelet transfusion. Conclusion: This study showed thrombocytopenia as a classic feature of vivax malaria presenting more than 80% of cases. In patients with profoundly low thrombocyte counts there was no manifestation of bleeding nor was any platelet transfusion required.
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