Mechanisms of Prooxidants in NeuroInflammatory Processes and Clinical Manifestations
Calderón Guzmán David, Juárez Olguín Hugo, Hernández García Ernestina, Osnaya Brizuela Norma, Saldivar González J. Alfredo
Annual Research & Review in Biology · pp. 3949–3961 · Published 17 Jul 2014
10.9734/ARRB/2014/11696Abstract
In clinic practice the reduction of cerebral blood flow in particular zones of the brain as brainstem can cause early cerebral damage then, ischemia and posterior reperfusion induce an inflammatory response leading to further cellular death. Indeed, inflammatory cells may release deleterious compounds or cytokines that exacerbate oxidative damage to metabolically compromised neurons, and similar mechanisms may operate in the pathophysiology of neurodegenerative diseases in which vascular factors, inflammation and oxidative stress are implicated. In the present work, the issue referent to mechanisms of pro-oxidants in inflammatory processes, and its relation with common pathogenesis and clinical manifestations are analyzed in detailed and updated form.
Cited by 2
David Calderón Guzmán, Norma Osnaya Brizuela, Maribel Ortiz Herrera · International Journal of Neuroscience · 2020
David Calderón Guzmán, Maribel Ortiz Herrera, Norma Osnaya Brizuela · Autonomic Neuroscience · 2017
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