Long-term Outcome of Splenectomy in Immune Thrombocytopenia (ITP)
Asian Hematology Research Journal · pp. 112–115 · Published 15 Apr 2023
Abstract
ITP is a chronic illness with frequent mucosal bleeding. Though the first line treatment is corticosteroids, relapse is frequent which necessitates splenectomy. Response to splenectomy is usually good initially; however, over the years relapses are frequent. Drugs then used are azathioprine, mycophenolate mofetil, anti-D globulin, TPO-receptor agonists, rituximab, cyclosporine, etc. Ultimately there is a small subset of patients who may require a small dose of prednisolone lifelong.
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