The Effect of Curcumin on the Invasion and Migration of Glioma Cells
Manar Zraikat, Munir Gharaibeh, Tasneem Alshelleh
European Journal of Medicinal Plants · pp. 11–16 · Published 27 Apr 2020
10.9734/ejmp/2020/v31i730249Abstract
Aim: This study investigated the effect of curcumin, from Curcuma longa, on the invasion of U87 glioma cell line spheres in 3D collagen model. Furthermore, this study investigated the anti-migration effects of curcumin on the migration of the same cell line in scratch assay. Place and Duration of Study: Department of Pharmacology, School of Medicine, The University of Jordan, Amman, Jordan, between March 2019 and May 2019. Methods: 3D invasion assay and 2D migration assays were used to fulfill these aims in addition to the Image J program that was used to analyze the area of invasion and the area of migration over the days of applying the assays. Results: The results showed an inhibitory effect of curcumin in all samples tested on both the invasion and migration of U87 cell line. Conclusion: This work adds more proofs on the importance of curcumin as anti-invasive and anti-migration agent and opens the door for more investigative studies.
Cited by 1
1 citation reported by external sources — individual citing-article records aren't available to list yet.
Related research
- In vitro Proliferation and Wound Healing Effects of Narcissus tazetta L. Bulb on Primary Human Dermal Fibroblasts — shares topic coverage
- Low-grade Gliomas in Children — shares topic coverage
- The Effects of Curcuma longa in Insulin Resistance — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
1
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.