Cytogenetic Studies of Recurrent Miscarriage- A Review
Yamini Pokale, Prashant Khadke
International STD Research & Reviews · pp. 1–18 · Published 9 Jan 2016
10.9734/ISRR/2016/23441Abstract
Recurrent miscarriage occurs in 1–3% of couples aiming at childbirth. It continues to be a challenging reproductive problem for the patient and clinician. Therefore, identifying a cytogenetic cause for a miscarriage may be of great significance for the management of recurrent miscarriage patients. Genetic factors in the form of chromosomal abnormalities, inherited Thrombophilia, single gene disorders and other genes involved are the main causes of recurrent miscarriage. The risk of miscarriage is highest among couples where the woman’s age is 35 years or above and men’s age is more than 40 years. Constitutional chromosomal abnormalities with great risk to be transmitted to offspring are rare, but their discovery is of crucial importance in prevention of spontaneous abortion and recurrent miscarriage.
Cited by 4
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Alisandra Morales de Machín, Karelis Urdaneta, Lisbeth Borjas · Revista de Obstetricia y Ginecología de Venezuela · 2021
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