Updated Approaches to the Management of Complicated Peptic Ulcer Disease: A Narrative Review Focus on Bleeding, Perforation and Obstruction

Abstract

Complicated peptic ulcer disease are complications that occur from peptic ulcer disease and can be divided into bleeding peptic ulcer, perforated peptic ulcer and gastric outlet obstruction. The diagnosis and management of this condition is important, as bleeding peptic ulcer disease is managed by endoscopy and medical therapy. Perforated gastric ulcer is primarily treated by surgical closure of the ulcer which can be performed by an open or laparoscopic method. Gastric outlet obstruction is managed by endoscopic ballon dilatation with surgical bypass being reserved for failure of medical therapy. As complicated peptic ulcer is associated with a significant morbidity and mortality, we have conducted this review article to look at the management of complicated peptic ulcer disease.