Amniotic Membrane Graft in Ocular Cicatricial Pemphigus: A More Conservative Approach

Abstract

Purpose: To report more conservative management of ocular cicatricial pemphigus (OCP) lesions by performing an initial corneal partial amniotic membrane graft without disturbance of the inflamed conjunctiva. Methods: A case report of a patient having a stage 3 OCP in his left eye with a corneal ulcer. He was managed by partial corneal amniotic membrane (AM) graft. Results: The course was favorable with complete corneal ulcer healing and incidentally there was an important regression of associated ocular surface inflammatory signs with a less prominent inferior symblepharon strand. Conclusion: We propose to manage newly diagnosed patients having advanced ocular cicatricial pemphigus disease with partial corneal amniotic membrane graft before performing radical adnexal surgery with prior immunosuppressive treatment.