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Research Article Open access CC BY 4.0

Epidemiological and Clinical Profile of Severe Malaria in Children Aged 6 Months to 15 Years at the Koutiala Regional Hospital in Mali

Sacko Karamoko, Waigalo Cheick, Kalirou Traoré, Maiga Belco, Konaré Hawa, Konaté Djeneba, Dembélé Adama, Touré Amadou, Traoré Fousseyni, Dembele Salif, Dembélé Hawa, Coulibaly Oumar, Cissé Mohamed Elmouloud, Togo Pierre, Doumbia Abdoul Karim, Maiga Leyla, Sidibé Lala N’drainy, Doumbia Aminata, Ouattara Arouna, Traore Bory, Coulibaly Yacouba, Simaga Tati, Ahamadou Ibrahim, Sangaré Aboubacar, Diakité Abdoul Aziz, Dicko Fatoumata, Togo Boubacar, Sylla Mariam

Asian Journal of Pediatric Research · pp. 30–36 · Published 4 Nov 2025

10.9734/ajpr/2025/v15i11487

Abstract

In Mali, malaria is endemic in the central and southern regions and has an epidemic potential in the later. Objective: to describe the epidemiological, clinical and therapeutic aspects of severe and complicated malaria in children aged between 6 months and 15 years in paediatric wards at the Koutiala regional hospital. Material and Methods: This was a prospective cross-sectional study conducted from 1st April 2018 to 31st March 2019 among children aged 6 months to 15 years old hospitalised for severe malaria. Data analysis was performed with SPSS version 18 software and word processing with Microsoft Word and Excel 2016 software. Results: Severe malaria accounted for 10% of hospital admissions (1280 cases/12441consultations), the sex ratio was 1.09 and children aged between 6 and 59 months represented 75.9% of patients.It is the second cause of hospitalisation after pulmonary tract infections. Severe anaemic malaria was the most common form, accounting for 54.69% of cases, followed by neurological malaria (29.64%) and hypoglycaemia (7.19%). At discharge, 90% of patients had no sequelae, 2% had sequelae, and the case fatality rate was 8%. Conclusion: Severe malaria accounted for 10% of hospital admissions. The main clinical signs on admission were fever in 83.83% of cases. Severe anaemic malaria was the most common form, accounting for 54.69% of cases

Haemolytic erythrocytopathy Malaria immunity insecticide

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