Aims: A simple and sensitive high performance liquid chromatographic (HPLC) method was developed for quantification of salbutamol in rat plasma. Terbutaline was used as an internal standard (IS). Study Design: Validation study. Methodology: The present method used solid phase ext...
Open access
Research Article10.9734/BJPR/2012/1279
Aims: To carry out the antistaphylococcal activity of n-butanol and aqueous sub-fractions of Alchornea cordifolia (Schumach. And Thonn.) Müll. Arg. leaf extract against multidrug resistant Staphylococcus aureus. Study Design: Characterization and antibiotic susceptibility determi...
Open access
Research Article10.9734/BJPR/2012/1727
Aim: To investigate the antiviral property of flavonoids from Cucumis metuliferus fruit pulp in chicken embryo fibroblast (CEF) cells and embryonated chicken eggs (ECE) induced with infectious bursal disease virus (IBDV). Study Design: Extraction and administration of bioactive e...
Open access
Research Article10.9734/BJPR/2012/1872
Aims: The crude ethanolic leaf extract of Bacopa monnieri (L) Penn. (family: Scrophulariaceae) was evaluated for its possible phytochemical nature (group determination of plant constituent) and selected pharmacological activities (analgesic, antidiarrhoeal and cytotoxic activity)...
Open access
Research Article10.9734/BJPR/2012/1951
Aim: To explore the ulceroprotective and antioxidant potential of Hyssopus officinalis in ethanol-induced gastric ulcer in rats. Study Design: Administration of plant extract and evaluation of antiulcer activity. Place and Duration of Study: Department of Pharmacology, Rayat Inst...
Open access
Research Article10.9734/BJPR/2012/1930
Recently, the residues or by-products of agriculture industry take attention for their valuable source of natural antioxidants. Taif rose (Rosa damascena trigintipetala Dieck) is considered one of the most important economic products of Taif, Saudi Arabia. In this study, the anti...
Open access
Research Article10.9734/BJPR/2012/1493
Aims: The purpose of this in vitro and ex vivo study was to prepare and characterise ocular minitablets of piroxicam based on different polymeric matrices and to evaluate their potential to provide prolonged and controlled drug release to ocular tissues after surface administrati...
Open access
Research Article10.9734/BJPR/2012/1653
Aims: To determine the effect of Piper sarmentosum (Ps) leaf extract on biomechanical strength and trabecular structure of the bones of glucocorticoid-induced osteoporotic rats. Study Design: Administration of crude extract to rats with excessive glucocorticoids. Place and Durati...
Open access
Research Article10.9734/BJPR/2012/1435
Aims: To investigate the petroleum ether extract of the unripe fruit of Solanum macrocarpum L. (Solanaceae) for its chemical components and its antimicrobial properties against Gram positive, Gram negative bacteria and fungi. Study Design: Experimental study. Place and Duration o...
Open access
Research Article10.9734/BJPR/2012/1207
Aims: To evaluate the effects of aqueous extract of V. amygdalina on lipid profile and lipid peroxidation status in rats. Study Design: Experimentation. Place and Duration of Study: Departments of Biochemistry and Pharmaceutical Chemistry, University of Benin, Benin city, Nigeria...
Open access
Research Article10.9734/BJPR/2012/1095