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Journal of Pharmaceutical Research International

Published by SCIENCEDOMAIN international · ISSN (electronic) 2456-9119

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7,450

Articles indexed

84

2026 articles

7,450

Open access

20,711

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Articles (7450)

Ameliorative Effect of Leaves of Carica papaya in Ethanol and Antitubercular Drug Induced Hepatotoxicity

Aashish Pandit, Tarun Sachdeva & Pallavi Bafna · Journal of Pharmaceutical Research International · 2013

Aims: The leaves of Carica papaya Linn. (Caricaceae) have been traditionally used as a medicine against some forms of liver diseases. Its hepatoprotective activity against hepatotoxicants like CCl4 and paracetamol has been scientifically proved in animals. The aim of the present...

Open access Research Article 10.9734/BJPR/2013/4517

Immunomodulatory Effects of Aqueous Extracts of Auricularia sp and Pleurotus sp Mushrooms in Cyclophosphamide-Immunosuppressed Wistar Rats

A. H. Kyakulaga, P. E. Ogwang, C. Obua, G. Nakabonge & E. N. Mwavu · Journal of Pharmaceutical Research International · 2013

Aims: To determine the immunomodulatory effect of aqueous extracts of Auricularia sp and Pleurotus sp mushrooms using an immunosuppression animal model. Study Design: Pre-clinical experimental study. Place and Duration of Study: Department of Pharmacology and Therapeutics, Colleg...

Open access Research Article 10.9734/BJPR/2013/1994

Antioxidant and Antitumor Activity of Plumeria acuminata in Ehrlich Ascites Carcinoma Bearing Swiss Albino Mice

Gomathi Periyasamy, Malaya Gupta, Upal Kanti Mazumder, Mebrahtom Gebrelibanos & Biruk Sintayehu · Journal of Pharmaceutical Research International · 2013

Aim: This study was designed to determine the antitumor and antioxidant properties of crude methanol extract from the leaves of Plumeria acuminata (Apocynaceae) (MEPA) against Ehrlich Ascites Carcinoma (EAC) bearing Swiss albino mice. Study Design: Study design is methodology, me...

Open access Research Article 10.9734/BJPR/2013/4472

Study of Fluconazole Release from O/W Cream and Water Soluble Ointment Bases

Aml I.A.A. Mekkawy, M. Fathy & Sohair El-Shanawany · Journal of Pharmaceutical Research International · 2013

Aims: Study the release of fluconazole from different O/W creams and PEG ointments. Study Design: In this study, different formulations were prepared with changing one of the added excipients and study the effect of this change on the drug release and then the selected formulatio...

Open access Research Article 10.9734/BJPR/2013/3702

Chronic Anti-Inflammatory Activity of Ethanolic Extract of Leaves of Clerodendrum viscosum by Carrageenin Induced Paw Oedema in Wistar Albino Rats

Chandrashekar R. & S. N. Rao · Journal of Pharmaceutical Research International · 2013

Aims: The aim of the study was to investigate chronic anti-inflammatory activity of ethanolic extract of the leaves of Clerodendrum viscosum (EELCV) by carrageenin induced paw oedema in Wistar albino rats. Study Design: Prospective. Place and Duration of Study: Dept of Pharmacolo...

Open access Research Article 10.9734/BJPR/2013/3505

Susceptibility Profile of Methicillin-Resistant Staphylococcus aureus (MRSA) Isolates to Antibiotics and Methanolic Extracts of Parkia biglobosa (Jacq) Benth

A. F. Obajuluwa, J. A. Onaolapo, A. R. Oyi & B. O. Olayinka · Journal of Pharmaceutical Research International · 2013

Aims: To study the susceptibility profile of methicillin-resistant Staphylococcus aureus (MRSA) isolates from orthopaedic patients to antibiotics and methanolic extracts of Parkia biglobosa. Background: Antimicrobial resistance in Staphylococcus aureus has attained alarming propo...

Open access Research Article 10.9734/BJPR/2013/2080

Optimization of Gabapentin Release and Targeting Absorption, Through Incorporation into Alginate Beads

Pierre A. Hanna, Shadeed Gad, Hassan M. Ghonaim & Mamdouh M. Ghorab · Journal of Pharmaceutical Research International · 2013

Aims: 1) To study the effect of some formulation variables on drug load, encapsulation efficiency, swelling ratio, mucoadhesion and drug release. 2) Optimize the mucoadhesion capabilities for targeting drug absorption and release-controlling capabilities of alginate beads. Method...

Open access Research Article 10.9734/BJPR/2013/3020

Hepatoprotective Effect of Drynaria quercifolia Fronds Hydroalcoholic Extract and Isolated Constituent against CCl4-Induced Hepatocellular Damage

Pradeep Kamboj & Ajudhia Nath Kalia · Journal of Pharmaceutical Research International · 2013

Aims: The present study was conducted to evaluate the hepatoprotective effect of hydroalcoholic extract of Drynaria quercifolia fronds (Dq), its fractions and isolated compound (Dq-4) from ethyl acetate (EA) fraction. Place and Duration of Study: Department of Pharmacognosy and D...

Open access Research Article 10.9734/BJPR/2013/3620

Block Copolymer Crosslinked Nanoassemblies Co-Entrapping Acridine Yellow and Doxorubicin for Cancer Theranostics

Pengxiao Cao, Andrei Ponta, JiAe Kim & Younsoo Bae · Journal of Pharmaceutical Research International · 2013

Aims: To develop block copolymer crosslinked nanoassemblies (CNAs) that co-entrap an imaging dye (Acridine Yellow: AY) and therapeutic agent (doxorubicin: DOX) as novel nanoparticle drug carriers for a combined application of drug delivery-based therapy and diagnostic imaging tec...

Open access Research Article 10.9734/BJPR/2013/4574

Free Radical Scavenging Activities of Nyctanthes arbor-tristis. L on Adjuvant Induced Arthritis in Rats

Smeera Thomas, J. Grace Nirmala & R. T. Narendhirakannan · Journal of Pharmaceutical Research International · 2013

Aims: The present study was undertaken to explore in vivo antioxidant potential of ethanol extracts of Nyctanthes arbor-tristis leaf and stem in adjuvant induced arthritic rats. Methodology: Arthritis induced rats were administered with extract of Nyctanthes arbor-tristis leaf an...

Open access Research Article 10.9734/BJPR/2013/3295