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Journal of Pharmaceutical Research International

Published by SCIENCEDOMAIN international · ISSN (electronic) 2456-9119

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7,450

Articles indexed

84

2026 articles

7,450

Open access

20,711

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Articles (7450)

Effects of Aqueous Extract of Some Selected Vegetables on Halofantrine Hepato-cardiatoxicity in Rats

A. J. Alhassan, M. S. Sule, A. M. Wudil & U. Lawan · Journal of Pharmaceutical Research International · 2014

Aim: The protective effect of some selected vegetables {Moringa (Moringa oleifera), Cabbage (Brassica oleracea) and Tomato (Solanum lycopersicum)} against hepato- cardio toxicity of halofantrine (an antimalarial drug) was evaluated in 72 albino rats. Study Design: The rats were g...

Open access Research Article 10.9734/BJPR/2014/7644

Comparative Studies of the Effect of Sphenocentrum jollyanum Pierre on High Fat and High Carbohydrate Diet Induced Obesity in Rats

Gabriel O. Anyanwu · Journal of Pharmaceutical Research International · 2014

Aim: The aim of this study was to compare the effect of ethanolic extract of Sphenocentrum jollyanum on high fat and high carbohydrate diet induced obesity in male wistar rats. Methodology: 30 male wistar rats used for this study were divided into 5 groups of 6 rats each. Group 1...

Open access Research Article 10.9734/BJPR/2014/10463

Evaluation of Thrombolytic Effect of Seven Different Bangladeshi Plants

Mohammed Abdullah Jainul, Shofiul Azam, Amin Chowdhury, Mohammad Mamun Ur Rashid, Abdullah Al Mamun & Hasibul Quader Chowdhury · Journal of Pharmaceutical Research International · 2014

Aim: From time past till date, proper documentation of the use of medicinal plants are helpful in drug development and research. The objective of this study is to evaluate several plant extracts of Bangladesh for their thrombolytic activity. Study Design: There are seven differen...

Open access Research Article 10.9734/BJPR/2014/6854

Development and Validation of UV Spectrophotometric Method for the Estimation of Haloperidol

Mohd Yasir & U. V. S. Sara · Journal of Pharmaceutical Research International · 2014

Aims: The aim of the present work was to develop and validate a sensitive, simple, accurate, precise & cost effective UV spectrophotometric method for the estimation of haloperidol in prepared pharmaceutical formulations of solid lipid nanoparticles. Methodology: The differen...

Open access Research Article 10.9734/BJPR/2014/10153

Phytochemical Testing and In vitro Antibacterial Activity of Bixa orellana (Annatto) Seed Extract

Modupeola Abayomi, Amusa S. Adebayo, Deon Bennett, Roy Porter, Janet Shelly Campbell & Garth Dawkin · Journal of Pharmaceutical Research International · 2014

Aim: The present study was designed to investigate the antibacterial activity of the seeds of Bixa orellana(Annatto, family Bixaceae) extracts. Methods: Powdered seed material was extracted using either organic solvents or acid-base protocols and the crystals obtained were washed...

Open access Research Article 10.9734/BJPR/2014/10925

Synthesis of Silver Nanoparticles and Incorporation with Certain Antibiotic Using Gamma Irradiation

A. I. El-Batal, Bakry M. Haroun, Ayman A. Farrag, Ahmad Baraka & Gharieb S. El-Sayyad · Journal of Pharmaceutical Research International · 2014

Aims: The study was explaining that silver nanoparticles (AgNPs) were synthesized biologically by Bacillus megaterium culture supernatant (as reducing and stabilizing agents) by the optimization of medium components for nitrate reductase production to enhance the synthesis of AgN...

Open access Research Article 10.9734/BJPR/2014/9566

Synthesis of Selenium Nanoparticles by Bacillus laterosporus Using Gamma Radiation

A. I. El-Batal, Tamer M. Essam, Dalia A. El-Zahaby & Magdy A. Amin · Journal of Pharmaceutical Research International · 2014

Aim: This study shows the possible synthesis of Selenium Nanoparticles (SeNPs) in aerobic optimized conditions using Bacillus laterosporus (B. laterosporus) bacterial strain. Methodology: B. laterosporus was used to reduce selenium ions (selenite anions) to SeNPs by fermentation...

Open access Research Article 10.9734/BJPR/2014/10412

Analysis of Fenoterol and Ipratropium Transfer from Human Lung Tissue into Human Plasma Using a Dynamic Dialysis Model

Beatrice Trammer, Boris Kardziev, Michael Schmidt & Petra Högger · Journal of Pharmaceutical Research International · 2014

Aims: The aim of the current study was to establish a simple and yet as much as possible physiologic approach for a simulation of the pulmonary absorption process to compare different inhaled drugs or drug formulations. Methodology: We designed a dialysis setting that allowed mon...

Open access Research Article 10.9734/BJPR/2014/9993

Anti Diabetic activity of Terminalia superba (Combretaceae) Stem Bark Extract in Streptozotocin Induced Diabetic Rats

Dzeufiet Djomeni Paul Désiré, Nguelefack Télesphore Benoît, Azay Jacqueline, Cros Gérard, Kamtchouing Pierre & Dimo Théophile · Journal of Pharmaceutical Research International · 2014

Aims: The present study was designed to evaluate the antidiabetic activity of the methanol stem bark extract of Terminalia superb (T. superba), a traditionally used medicinal plant in Cameroon. Place and Duration of Study: Departement of Animal Biology and Physiology, Faculty of...

Open access Research Article 10.9734/BJPR/2014/9163

UPLC-MS/MS Determination of Aceclofenac and Diclofenac in Bulk, Dosage forms and in At-line Monitoring of Aceclofenac Synthesis

Ramzia I. El-Bagary, Hassan M. E. Azzazy, Ehab F. ElKady & Faten Farouk · Journal of Pharmaceutical Research International · 2014

Aim: The derivatization product of diclofenac (DCL), aceclofenac (ACL), is a non-steroidal anti-inflammatory drug (NSAID) which causes faster and extended action with reduced gastrointestinal (GI) inflammation. The detection of DCL in ACL bulk and pharmaceutical products indicate...

Open access Research Article 10.9734/BJPR/2014/5676