Aim: To investigate the dichloromethane fraction obtained from an aqueous methanol extract of green stems of Citrus jambhiri Lush. and evaluate the hepatoprotective effect of limonianin. Study Design: Isolation and identification of secondary metabolite and hepatoprotective activ...
Open access
Research Article10.9734/BJPR/2014/12311
A series of new phthalimides 1(a-f) were synthesized via reaction phthalic anhydride with different amino acids under fusion conditions. Esterification of N-phthaloyl acid derivatives 1(a-f) with methanol in the presence of SOCl2 to producing the corresponding esters 2(a-f). Whic...
Open access
Research Article10.9734/BJPR/2014/6355
Aims: This study was design to screen the stem bark extract of Pseudocedrela kotschyi for the presence of phytochemical constituents and evaluate the extract for antimicrobial activity on wide range of pathogenic bacteria and fungi species. Place and Duration of Study: Department...
Open access
Research Article10.9734/BJPR/2014/12163
Md. Tauhid-Ul Islam, Md. Abdus Samad Bhuiyan, Md. Musfequr Rahman Shajjad, Md. Taimuzzaman Sharif, Md. Zakir Sultan, Asma Rahman, Md. Akter Hossain, Abu Asad Chowdhury & Mohammad Shah Amran·Journal of Pharmaceutical Research International·2014
Aims: The present study was designed to evaluate the anti-diabetic as well as prophylactic activity of Jambadyarista and Bohumutrantak Ras in alloxan-induced diabetic rats. Study Design: Study the prophylactic and antiglycemic effects against diabetes of two Ayurvedic drugs ‘Jamb...
Open access
Research Article10.9734/BJPR/2014/11521
Aims: Lemon grass and mango bark serves as one of the medicinal plants used in Nigeria for the treatment of malaria by traditional herbalists. This study was designed to assess the effects of ethanolic extract of lemon grass and mango bark on the cerebral astrocytes of wistar rat...
Open access
Research Article10.9734/BJPR/2014/11772
The acute toxicity of chloroform extract of Artemisia maciverae Linn was studied in Swiss albino mice. The mice were randomly distributed into four groups of three animals each. The groups were respectively administered both intraperitoneally and orally chloroform extract of Arte...
Open access
Research Article10.9734/BJPR/2014/7865
The present investigation targets to develop a simple, specific, sensitive and accurate reverse phase high performance liquid chromatographic (RP-HPLC) method in human plasma for the estimation of metformin HCl and propranolol HCl from bulk drug and also from the marketed product...
Open access
Research Article10.9734/BJPR/2014/10826
Extracts of St. John’s Wort (Hypericum perforatum) are known to cause interactions with certain conventional drugs. Herein, we focus on two clinically relevant concepts. First, St. John´s Wort has been used by people of all ages as an herbal treatment for depression without medic...
Open access
Research Article10.9734/BJPR/2014/9602
Tolterodine is an antimuscarnic drug that is used for sympathetic treatment of urinary incontinence. Tolterodine modified release tablet, was investigated in rabbit for pharmacokinetic and in vitro–in vivocorrelation studies. Tablets were prepared and in vitro release was studied...
Open access
Research Article10.9734/BJPR/2014/9950
Hypomagnesemia is one of the nephrotoxicity signs. In addition, renin-angiotensin system may be involved in pathophysiology of kidney diseases. Therefore, the present study was designed to investigate the possible role of losartan plus oral magnesium sulfate (MgSO4) to reduce CP-...
Open access
Research Article10.9734/BJPR/2014/10164