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Journal of Pharmaceutical Research International

Published by SCIENCEDOMAIN international · ISSN (electronic) 2456-9119

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7,450

Articles indexed

84

2026 articles

7,450

Open access

20,711

Citations (indexed)

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Articles (7450)

Natural Products as Potential Sources of Antidiabetic Drugs

Patience O. Osadebe, Estella U. Odoh & Philip F. Uzor · Journal of Pharmaceutical Research International · 2014

Natural products have played and continue to play an invaluable role in the treatment of various diseases and in drug discovery processes. It has remained a source of new compounds with diversified structural arrangements possessing interesting biological activities for various d...

Open access Research Article 10.9734/BJPR/2014/8382

Phytochemical, Nutrient Composition and Serum Lipid Lowering Effect of Xylopia aethiopica Fruit

Yusuf N. Omeh, Samuel O. Onoja, Maxwell I. Ezeja, S. Bassey, G. Ogbenta & Ayoade B. Adetayo · Journal of Pharmaceutical Research International · 2014

Aims: The present study was carried out to evaluate the effects of Xylopia aethiopica on serum lipids in fed rats. Also the quantitative phytochemical and nutrient composition was investigated. Study Design: Quantitative phytochemical, proximate analysis and in vivo effect on ser...

Open access Research Article 10.9734/BJPR/2014/12392

The Knowledge and Attitude of Practicing Dentists towards the Antibiotic Prescription: A Regional Study

Kamis Gaballah, Adel A. Bahmani, Anas Salami & Nageeb A. M. Hassan · Journal of Pharmaceutical Research International · 2014

Aims: To assess dentist’s knowledge and practice in relation antibiotic prescription and to investigate if they follow the current international guidelines. Methodology: In this cross sectional study a structured and pretested questionnaire was sent to 202 licensed dental practit...

Open access Research Article 10.9734/BJPR/2014/12520

Phytochemical Screening and Antibacterial Activity of Five Malaysian Medicinal Plants

Rasha Saad, Loshini Appalasamy, Jiyauddin Khan, Hamid Kazi, Eddy Yusuf & Fadli Asmani · Journal of Pharmaceutical Research International · 2014

Natural drugs play important and vital role in the modern medicine. It is usually used to cure some ailments which may not be treated by conventional medicine. Natural drugs may exhibit many biological activities, such as antimicrobial, anticancer, anti-diabetic and antioxidant....

Open access Research Article 10.9734/BJPR/2014/12233

Quantitative Phytochemical Evaluation of Stem Bark Extracts of Harungana madagascariensis

Fredrick Nwude Eze & Osamede Jennifer Airouyuwa · Journal of Pharmaceutical Research International · 2014

Aims: The study was conducted to quantify some phytochemicals present in hydroethanol (absolute ethanol: water 1:1 v/v) and methanol extracts of Harungana madagascariensis stem bark traditionally used in the management of diabetes mellitus. Methodology: Hydroethanol and methanol...

Open access Research Article 10.9734/BJPR/2014/9988

Antibacterial, Synergistic and β-lactamase Inhibitory Activity of Oroxylem indicum: An In vitro and Molecular Interaction Study

Anupma Malik, Sheema Bai, Leena Seasotiya, Pooja Bharti & Sunita Dalal · Journal of Pharmaceutical Research International · 2014

Aims: The study was aimed to evaluate the antibacterial, synergistic and β-lactamase inhibitory potential of O. indicum against ampicillin resistant and Extended Spectrum β-lactamase (ESBL) producing bacterial strains. Methods: Bacterial strains were screened for ampicillin resis...

Open access Research Article 10.9734/BJPR/2014/12343

Sterility and Radiostability of Amoxicillin and Cefaclor Antibiotics Sterilized by Gamma Irradiation

Abdelgawad M. Hashem, Hala N. Elhifnawi & Sara S. Farag · Journal of Pharmaceutical Research International · 2014

Aim: The present investigations aimed at studying the effect of sterilization by gamma irradiation on amoxicillin and cefaclor antibiotics. They have been irradiated in solid dry state and the probable changes in physicochemical and microbiological properties were studied Place a...

Open access Research Article 10.9734/BJPR/2014/12251

Physicochemical and Bioequivalence Studies on Some Brands of Levofloxacin Tablets Registered in Nigeria

Chukwuemeka Paul Azubuike & Samson Ojo Oluyase · Journal of Pharmaceutical Research International · 2014

Aims: This study was aimed at comparing the physicochemical and bioavailability profiles of some brands of Levofloxacin 500mg tablets that are registered in Nigeria by her regulatory authority and to examine the feasibility of interchangeability of the brands. Methodology: The ph...

Open access Research Article 10.9734/BJPR/2014/12355

Tegumental Changes in Adult Schistosoma mansoni Induced by a New Imidazolidinic Derivative

Anekécia Lauro da Silva, Sheilla Andrade de Oliveira, Jamerson Ferreira de Oliveira, Edna de Farias Santiago, Antônio Sérgio Alves de Almeida Júnior, Íris Trindade Tenório Jacobi, Christina Alves Peixoto, Vinícius Pinto Costa Rocha, Milena Botelho Pereira Soares, Ivan da Rocha Pitta & Maria do Carmo Alves de Lima · Journal of Pharmaceutical Research International · 2014

Aims: Verify the potential of the schistosomicidal imidazolidine derivative (5Z)-3-(4-bromo-benzyl)-5-(4-chloro-benzylidene)-4-thioxo-imidazolidin-2-one. Study Design: In this study, we tested the imidazolidinic derivative 3 through in vitro evaluations, cytotoxicity assay and an...

Open access Research Article 10.9734/BJPR/2014/12511

In vivo Anthelmintic Activity of Terminalia glaucescens (Combretaceae) Extracts against Gastrointestinal Nematodes of Sheep

Mbafor Fidelia Lem, V. Khan Payne, J. Wabo Poné, Mbogning Tayo Gertrude & J. Tchoumboue · Journal of Pharmaceutical Research International · 2014

Background: Gastrointestinal nematodes (GIN) are a major threat to sheep productivity and endanger animal welfare worldwide particularly in developing countries. They cause loss of production through mortality, weight loss, reduced milk, meat and wool production. Thus, parasitism...

Open access Research Article 10.9734/BJPR/2014/12936