Four simple and accurate spectrophotometric methods were developed for the simultaneous determination of paracetamol, pamabrom and pyrilamine maleate. The first is a zero order spectrophotometric method used for the determination of pyrilamine maleate in presence of paracetamol a...
Open access
Research Article10.9734/JPRI/2017/38353
Aims: Jatropha curcas (J. curcas) is a plant that has numerous medicinal and industrial applications. Evaluation of in vitro and in vivo acute/sub chronic hepato-renal toxicity of crude methanol J. curcas leaf extract on albino rats, in vitro toxicity of the fractions and charact...
Open access
Research Article10.9734/JPRI/2017/38137
Objective: The objective of this research is to investigate the analgesic and antipyretic activity of methanolic extract of Hemigraphis hirta. Methods: Whole dried plant of Hemigraphis hirta was extracted with pure methanol. Analgesic activity was tested by both acetic acid induc...
Open access
Research Article10.9734/JPRI/2017/37077
A novel method for evaluating antitermite activity was standardized whereby filter papers treated with 50% methanolic, 90% methanolic and aqueous extracts of Thevetia peruviana leaves from polluted and non-polluted sites against Odontotermes obesus. In vivo investigation was carr...
Open access
Research Article10.9734/JPRI/2017/37693
Present study was accomplished to prospect the viability of using the montmorillonite (Mon) nanoparticles as an adsorbent to remove the Ampicillin under various experimental conditions. The Physico-chemical characteristics of the studied adsorbent were surveyed. Langmuir, Freundl...
Open access
Research Article10.9734/JPRI/2017/38056
Aim: This work aims at investigating the effect of drying methods on the powder and compaction properties of microcrystalline cellulose (MCC) obtained from the matured fruit husk of Cocos nucifera (CN). Study Design: Experimental design. Place and Duration of Study: University of...
Open access
Research Article10.9734/JPRI/2017/37615
Objective: To investigate the antifungal, antioxidant and phytochemical screening of Melia azedarach flowers by using different solvents. Materials and Methods: Antifungal activity was experimented against three fungi (Aspergillus niger, Aspergillus fumigatus, Aspergillus flavus)...
Open access
Research Article10.9734/JPRI/2017/38246
Aim: This study used QSAR Pharmacophore-based virtual screening and molecular docking to identify lead compounds and determine structural requirements for breast cancer inhibitor development. CoMFA and CoMSIA modeling was employed to design more potential inhibitors. Materials an...
Open access
Research Article10.9734/JPRI/2017/37821
Aim: This study was designed to investigate the bioactive spice to determine its activity against some selected human bacterial pathogens. The spice studied was Ocimum gratissimum (clove basil). Place and Duration of study: Microbiology laboratory of Bells University of Technolog...
Open access
Research Article10.9734/JPRI/2017/37897
Aim and Objectives: To design, formulate and perform in vitro studies of a fixed dose combination (FDC) immediate release solid dosage form of the antihypertensive drugs atenolol, enalapril and hydrochlorothiazide. The objectives of the study were to perform pre-formulation studi...
Open access
Research Article10.9734/JPRI/2017/38019