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Journal of Pharmaceutical Research International

Published by SCIENCEDOMAIN international · ISSN (electronic) 2456-9119

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7,450

Articles indexed

84

2026 articles

7,450

Open access

20,711

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Articles (7450)

Synthesis and Ca2+-desensitizing Activity of 2-methyl-7-aryl(α-furyl)-[1,3]thiazolo[4,5-d]pyridazin-4(5H)-ones

Anatoly Soloviev, Sergey Demchenko, Ludmyla Bobkova, Valentyn Panchenko, Sergey Zelenskyi & Anatoly Demchenko · Journal of Pharmaceutical Research International · 2018

Aims: Search of new chemical compounds for pressure decrease in accordance with new mode of action. Study Design: Novel 2-methyl-7-aryl(α-furyl)-[1,3]thiazolo[4,5-d]pyridazin-4(5H)-ones were synthesized in 67-84% yields via reaction of 2-methyl-5-benzoyl(furoyl)-thiazol-4-carboxy...

Open access Research Article 10.9734/JPRI/2018/37338

Molecular Typing and Antimicrobial Susceptibility of Acinetobacter baumannii Isolates in Kermanshah City with Pulse Field Gel Electrophoresis (PFGE)

Parviz Mohajeri, Touraj Esmailzadeh, Sara Torkaman & Abbas Farahani · Journal of Pharmaceutical Research International · 2018

Background and Objective: Acinetobacter baumannii (A. baumannii) in the last decade has been identified as one of the opportunistic pathogens and an important cause of nosocomial infections. Molecular typing plays an important role in studying the epidemiology of Acinetobacter. T...

Open access Research Article 10.9734/JPRI/2017/39168

In vitro Proliferation and Wound Healing Effects of Narcissus tazetta L. Bulb on Primary Human Dermal Fibroblasts

Maryam Rameshk, Fariba Sharififar, Mitra Mehrabani, Abbas Pardakhty & Alireza Farsinejad · Journal of Pharmaceutical Research International · 2018

Aims: Narcissus tazetta L. bulbs have been used in Traditional Persian medicine (TPM), as "Zaroor" for wound healing. Toward quality assurance of the plant, pharmacognostic and phytochemical studies, physicochemical characterization, and healing effects of "Zaroor" were studied....

Open access Research Article 10.9734/JPRI/2017/39090

Effect of Resveratrol on Liver Histopathology of Lead-induced Toxicity in Wistar Rats

Salisu Muhammad Highab, Musa Aliyu & Bala Yauri Muhammad · Journal of Pharmaceutical Research International · 2018

Aims: To investigate the effect of resveratrol on liver histopathology of lead-induced toxicity in wistar rats. Study Design: Experimental Study. Place and Duration of Study: Department of  Pharmacology and  Therapeutics, Ahmadu Bello University, Zaria (11° 10' N, 07° 38' E), at...

Open access Research Article 10.9734/JPRI/2017/23253

Antioxidant and Anti-urease Activity of Various Solvent Extracts of “Terminalia arjuna” Seeds

Naila Aslam, Mahmood Ahmad, Kashif Barkat & Muhammad Khawar Abbas · Journal of Pharmaceutical Research International · 2018

Background: Terminalia arjuna, a popular cardio curative plant. Present work emphasizes on the evaluation of antioxidant and anti-urease activity of different fractions extracts of Terminalia arjuna seeds. Methods: Six alternate fractions including methanol, ethanol, n- butanol,...

Open access Research Article 10.9734/JPRI/2017/38794

Application of Molecular Techniques in Quality Control of Drugs of Natural Origin; A Review

Juwairiya Butt, Shumaila Arshad, Zulfiqar Ali Mir, Sophia Awais, Javed Iqbal & Saeed-Ul-Hassan . · Journal of Pharmaceutical Research International · 2018

Pharmacognosy is a long established pharmaceutical science, which played a diverse role in the discovery, characterization, production and standardization of drugs. Molecular pharmacognosy using molecular biological tools has extended the scope of pharmacognostical science and pl...

Open access Research Article 10.9734/JPRI/2017/38523

A Review on Tablet Scoring: Background, History and Current Regulatory Considerations

Maitri R. Trivedi, Hardikkumar H. Patel & Rutesh H. Dave · Journal of Pharmaceutical Research International · 2018

Tablet splitting or breaking of tablets into multiple strengths has been a common practice across the world. Splitting of tablet offers various advantages such as dose flexibility and ease of swallowing in different population including geriatric and pediatric patients (wide pati...

Open access Research Article 10.9734/JPRI/2017/39027

Ciprofloxacin Antibiotics Removal from Effluent Using Heat-acid Activated Red Mud

Davoud Balarak, Ali Joghataei, Ferdos Kord Mostafapour & Edris Bazrafshan · Journal of Pharmaceutical Research International · 2018

In this study, the adsorption of Ciprofloxacin (CIP) antibiotics from a synthetic solution containing CIP is investigated using Red Mud (RM) and Red Mud that is activated by HCL (ARM). Scanning Electron Microscopy (SEM) techniques are used to morphological characteristics of Red...

Open access Research Article 10.9734/JPRI/2017/38974

Investigations into Antibacterial, Phytochemical and Antioxidant Properties of Vitellaria paradoxa (Gaertn.) Stem Bark Extracts

Oluwaseun Oyetunji Olasunkanmi, David Ayinde Akinpelu, Paul Opeyemi Adeniyi, Oludare Femi Ajayi, Joseph Omololu-Aso & Felix Oluwasola Olorunmola · Journal of Pharmaceutical Research International · 2018

This study investigated the antibacterial potentials and mechanisms of action of crude extract and fractions from stem bark of Vitellaria paradoxa on susceptible bacterial isolates. It also assessed the phytochemical constituents and antioxidant properties of the plant. This was...

Open access Research Article 10.9734/JPRI/2017/38749

Screening and Production of Peptidase Producing Bacillus Species Isolated from Soil

Shahpara Rehman, Rimsha Khan, Syed Bilal Hussain & Syed Aun Muhammad · Journal of Pharmaceutical Research International · 2018

Aims: Proteases are the most deliberate microbial enzyme at mercantile, industrial, health professional, analytic, symptomatic, outgoing interruption and other sectors. Methodology: About 8 isolates were recovered from different soil samples gathered from various fields of Abdul...

Open access Research Article 10.9734/JPRI/2017/37048