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Journal of Pharmaceutical Research International

Published by SCIENCEDOMAIN international · ISSN (electronic) 2456-9119

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7,450

Articles indexed

84

2026 articles

7,450

Open access

23,697

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Articles (7450)

The Effect of Ethanol Extract of Carica papaya Seed towards Lipid Profile on Rats Induced Rifampicin and Isoniazid

. Liana, I. Nyoman Ehrich Lister, Edy Fachrial & . Adrian · Journal of Pharmaceutical Research International · 2021

Aims: Rifampicin one of the most commonly used front-line drugs in antituberculosis therapy, has been known to be hepatotoxic. The oxidative stress that is formed in the mitochondria due to rifampicin and isoniazid causes an imbalance in lipid metabolism. This study aims to deter...

Open access Research Article 10.9734/jpri/2021/v33i41A32320

Dapsone Induced Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) Syndrome - A Case Report

Safi Eldin E. Ali, Osama M. Ibrahim & Sami F. Abdalla · Journal of Pharmaceutical Research International · 2021

A 50-year-old male Sudanese patient presented with a three-week history of jaundice, high-grade fever, and mucocutaneous eruption. For last months he was on compound therapy for leprosy, which had been confirmed recently. The patient’s face was prominent, along with the erythemat...

Open access Research Article 10.9734/jpri/2021/v33i41A32309

Malnutrition and Some Related Factors in Primary School Children in Saudi Arabia: Systemic Review

Hassan Tag Elkhatim Mohamed, Fahad Salamah Obaid Alanazi, Salah Farhan T. Alanazi, Mohammed Naif H. Aljuraysi & Omar Ayed B. Alanazi · Journal of Pharmaceutical Research International · 2021

Background: Malnutrition is an underlying factor in many diseases in both children and adults, and it contributes greatly to the disability-adjusted life years worldwide. It is a major public health concern in developing countries among children since it places a heavy burden on...

Open access Research Article 10.9734/jpri/2021/v33i41A32310

Prevalence and Expression of Genes of Type II Antitoxin Toxin Systems in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus

M. Rahimkhani, A. Mordadi, P. Karami & O. Zarei · Journal of Pharmaceutical Research International · 2021

Objectives: Antibiotic resistance of bacteria has been increasing in recent years and reports indicate that some bacterial strains are even resistant to the last treatment line. The survey of MazEF antitoxin-toxin genes in 84 strain of MRSA and and the antimicrobial effect of sup...

Open access Research Article 10.9734/jpri/2021/v33i41A32307

A Cross Sectional Study to Assess the Status of Hemoglobin and Other Blood Indices among Pregnant Women Attending Tertiary Care Hospital of Vadodara

Vruti Patel & J. D. Lakhani · Journal of Pharmaceutical Research International · 2021

Introduction: A number of adaptations happen in the anatomy, physiology and metabolic processes within the mother which aids in successful progression of the pregnancy. The different blood indices such as haemoglobin concentration, packed cell volume (PCV), red blood cell count;...

Open access Research Article 10.9734/jpri/2021/v33i41A32308

Capsaicin Encapsulated Chitosan Nanoparticles Augments Anticarcinogenic and Antiproliferative Competency Against 7,12 Dimethylbenz(a)anthracene Induced Experimental Rat Mammary Carcinogenesis

Kalaiyarasi Dhamodharan, Manobharathi Vengaimaran & Mirunalini Sankaran · Journal of Pharmaceutical Research International · 2021

Background: Capsaicin is a powerful phytochemical spotted in chilies, starkly tied up with a bunch of health benefits but its clinical applications in cancer therapy are limited due to its poor solubility, and low bioavailability. Nanotechnology offers a strategy to discover new...

Open access Research Article 10.9734/jpri/2021/v33i41A32311

Effects of Spider Cage Therapy in Combination with Conventional Speech Therapy on Speech and Language Function in Children with Cerebral Palsy of Age between 05 and 15 Years

Fahad Masood, Muhammad Sikander Ghayas Khan, Farjad Afzal, Amna Rashid & Saba Mubarak · Journal of Pharmaceutical Research International · 2021

Objective: The objective of study was to determine the effects of spider cage therapy in combination with conventional speech therapy on speech and language function in children with cerebral palsy of age between 05 And 15 Years. Materials and Methods: A total of 20 children from...

Open access Research Article 10.9734/jpri/2021/v33i41A32312

In-vitro Cytoprotective Activity of Eichhornia crassipes Flowers Against Hydrogen Peroxideinduced Oxidative Stress in BRL 3A Rat Liver Cells

S. Rajarajan, S. Sivakrishnan & V. Ganesan · Journal of Pharmaceutical Research International · 2021

The aim of this study was to investigate the cytoprotective effect of ethanol extract of Eichhornia crassipes flowersand its fractions against hydrogen peroxide induced oxidative stress in BRL 3A liver cells. Powdered flowers of Eichhornia crassipeswere subjected to hot continuou...

Open access Research Article 10.9734/jpri/2021/v33i41A32313

The Role of SGLT-2 Inhibitors as an Adjuvant to Insulin Therapy in Type-1 Diabetes Mellitus- Literature Review

Sultan Ali Alshehri, Sultan Abdulwahab M. Asiri, Aalaa Mohammad Algarni & Manal Mohammed Alamari · Journal of Pharmaceutical Research International · 2021

Background: Type 1 diabetes mellitus is the main risk factor for cardiovascular complications. Therefore, intensified insulin therapy might be needed to achieve better glycemic control in some patients. However, insulin therapy might lead to increase body weight and induce hypogl...

Open access Research Article 10.9734/jpri/2021/v33i40B32295

Development and Validation of Novel RP-HPLC Method for the Simultaneous Determination of Remogliflozin and Vildagliptin in Bulk and in synthetic Mixture

Drashti A. Mandale, Chainesh Shah & Rakesh Jatt · Journal of Pharmaceutical Research International · 2021

Vildagliptin which is DPP-4 inhibitor and Remogliflozin which is SGLT2 inhibitor in single dose regimen lower blood glucose by separate, complementary mechanisms. Both are glucose dependent, accounting for the low risk of hypoglycaemia during treatment. There is no risk factors a...

Open access Research Article 10.9734/jpri/2021/v33i40B32296