Memantine hydrochloride is a is a reversible cholinesterase inhibitor used in the treatment of Alzheimer’s disease, low-moderate affinity, uncompetitive n-methyl-d-aspartate (NMDA) receptor antagonist, with strong voltage dependency and rapid blocking/unblocking kinetics. The pre...
Open access
Research Article10.9734/jpri/2021/v33i41B32374
Background: Type 1 diabetes mellitus leads to significant cardiovascular risk through various mechanisms. Intensified insulin therapy is commonly required to achieve adequate glycemic control and reduce HbA1c. However, when insulin dose increases, it might increase insulin resist...
Open access
Research Article10.9734/jpri/2021/v33i41B32357
Adolescent mental wellbeing is a serious and un-recognized public health concern. Adolescent depression is widespread, but many may not have convenient accessibility to mental health resources. If they are diagnosed and handled early on, there is a greater likelihood of a good lo...
Open access
Research Article10.9734/jpri/2021/v33i41B32359
Aims and Objectives: There is lack of understanding of distinct molecular pathways and associated gene mediators of the Potentially malignant disorders of the oral cavity (OPMD), such as Leukoplakia and Oral sub mucous fibrosis. This microarray data analysis aims to highlight com...
Open access
Research Article10.9734/jpri/2021/v33i41B32356
The present study is performed with the purpose of evaluating the antioxidant nature of Moringa Oleifera leaves and the effectiveness of the leaf extract against the disease called Rheumatoid Arthritis. The disease is very chronic and it is a common disease. So the study is focus...
Open access
Research Article10.9734/jpri/2021/v33i41B32358
This study was aimed at evaluating the serum levels of Calcium, Inorganic phosphate and Magnesium together with the Body Mass Index (BMI) in lactating mothers in Owerri. A total of sixty subjects were recruited. Thirty were lactating subjects while thirty were apparently healthy...
Open access
Research Article10.9734/jpri/2021/v33i41B32360
Aim: The present study was aimed to investigate “Effects of Solvents and Extraction Methods on Naringenin, HPLC Based Quantitative Studies and major Metabolite of Cochlospermum Gossypium”. Study Design: HPLC based Quantification Studies. Place and Duration of Study: Department of...
Open access
Research Article10.9734/jpri/2021/v33i41B32361
The study aims to analyse the effects of Wi-Fi radiations from mobile phone towers on the level of salivary cortisol , its effects on cardiovascular system , and on the cognitive levels of the subjects. on thirty six subjects exposed to Wi-Fi radiation from mobile phone tower (Gr...
Open access
Research Article10.9734/jpri/2021/v33i41B32362
Aims: The Drug-Excipient compatibility testing was conducted at an early product development stage to determined that Excipients were compatible with drugs used in formulation and to distinguish as many degradation products as possible using validated gradient RP-HPLC method. Stu...
Open access
Research Article10.9734/jpri/2021/v33i41B32363
Background: Adiponectin (APN) is a novel hormone produced mainly by white adipose tissue that contribute to various physiological functions. APN has been related to cancer development specially the ones related to obesity such as breast cancer (BC) and colorectal cancer (CRC). Th...
Open access
Research Article10.9734/jpri/2021/v33i41B32364