Aims: To determine the role of human beta defensin-2 and oxidative stress by measuring serum human beta defensin-2 and antioxidant parameters in ovarian cancer patients. Study Design: Serum human beta defensin-2 (HBD-2), and the levels of antioxidants such as serum superoxide dis...
Open access
Research Article10.9734/IJBCRR/2013/5105
Aberrant Jagged1-mediated Notch activation is linked to cancer and induces epithelial-to-mesenchymal transition through the repression of E-cadherin transcription. All three proteins are subject to sequential proteolytic events referred to as regulated intramembrane proteolysis....
Open access
Research Article10.9734/IJBCRR/2013/3847
Purpose: This study was conducted to assess the effect of the ethyl acetate fraction (AcEF1) obtained from the 96% extract of Morinda morindoides extract on cardiac tissue integrity and function in rabbits. Methodology: The rabbits were divided in five groups of 6 rabbits e...
Open access
Research Article10.9734/IJBCRR/2013/4251
Aims: The present paper aims to study the effect of aromatic structure on the inhibition of biogas production and more specifically the effect of para substituted anilines functional groups (chemical structure) on methane biosynthesis by the digested pig manure methanogens. The o...
Open access
Research Article10.9734/IJBCRR/2013/2458
Glutathione S-transferase enzyme (GSTT1 and GSTM1) gene polymorphisms have been associated with the genetic susceptibility to end stage renal disease (ESRD) in different populations. We investigated the association between GSTT1 and GSTM1 genes, and ESRD in Egyptian population. T...
Open access
Research Article10.9734/IJBCRR/2013/4464
Aims: To evaluate anti-diabetic and liver enzymes activities of aqueous extracts of Moringa oleifera and Bridelia ferruginea leaves in alloxan induced diabetic albino rats. Study design: Diabetes was induced in three groups of rats, one group was not treated while two groups were...
Open access
Research Article10.9734/IJBCRR/2013/3859
Osteoporosis is a major health concern that is associated with an increased risk of first and subsequent bone fractures. Untreated osteoporosis results in considerable morbidity. Currently, bisphosphonates are the mainstay of treatment for osteoporosis and the aim of this study w...
Open access
Research Article10.9734/ijbcrr/2013/4210
Aim: To analyze the active sites of various prokaryotic and eukaryotic DNA polymerases and propose a plausible mechanism of action for the polymerases with the Escherichia coli DNA polymerase I as a model system. Study Design: Bioinformatics, Biochemical and X-ray crystallographi...
Open access
Research Article10.9734/IJBCRR/2013/3777
The chemical parameters of glucose syrup produced from five different weight ratios of sorghum malt and sweet potato flour using sorghum malt as a source of enzyme hydrolysis were studied. There were variations in the chemical parameters of the samples as a result of the differen...
Open access
Research Article10.9734/IJBCRR/2013/2247
Aims: The effects of oral administration of aqueous leaf extract of Ocimum gratissimum (OG) on biliary and serum bilirubin, cholesterol and electrolytes in streptozotocin (STZ)-induced diabetic Albino Wistar rats was studied. Methodology: Type 1 Diabetes mellitus was induced in t...
Open access
Research Article10.9734/IJBCRR/2013/4258