Aims: To formulate and characterize GLB-PEG-LEC NCs (lecithin complexed Glibenclamide nanocrystals) and to analyze the effect of PEG 20000 and lecithin on drug properties, particle size reduction and stability of GLB NCs. Study Design: Precipitated (GLB-PEG) and complexed nanocry...
Open access
Research Article10.9734/BJPR/2013/5515
Aims: Hiptage benghalensis is used in the traditional system of medicine. The leaf is considered one of the important plant organs for the treatment of various diseases such as rheumatism, leprosy, wounds, ulcer, burning sensation, scabies, inflammation and cough. Hence, the pres...
Open access
Research Article10.9734/BJPR/2013/4454
Aims: Brain and spinal cord tumors are the third most common type of childhood cancer following leukemia and lymphoma. Mechlorethamine (or mustine) is a nitrogen mustard antineoplastic drug. Eleven variants of mechlorethamine are presented that possess molecular properties enabli...
Open access
Research Article10.9734/BJPR/2013/5761
Aims: To investigate the effect of ethanol extract of Coccinia grandis Lin (Cucurbitaceae) leaf in glucose and cholesterol lowering activity in animal model. Study Design: Extraction, glucose and cholesterol lowering activity evaluation. Place and Duration of Study: Department of...
Open access
Research Article10.9734/BJPR/2013/4583
We performed studies to correlate the biological activity of the TIBO (4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-j,k][1,4] benzodiazepin-2(1H)-one)14 sets of compound with the independent variable (descriptor) to know the structural requirement of the drug receptor binding interac...
Open access
Research Article10.9734/IRJPAC/2013/2817
The oligomerization process of pyrocondensate fraction was performed in the presence of catalytic systems which were synthesized by the reaction of aluminium metal (Al) and dichloroethane (DCE) as the basic catalyst and after that were modified with metal chloride of Mn (II), Fe...
Open access
Research Article10.9734/IRJPAC/2013/4757
This present work is a report on the stability constant values of a worthy antibiotic, Ampicillin Trihydrate; D[-]-α-aminobenzyl penicillin; ABP; a semi-synthetic derivative of penicillin with various biologically vital bivalent metal ions (Co2+, Ni2+, Cu2+, Zn2+, Cd2+, Sn2+, Hg2...
Open access
Research Article10.9734/IRJPAC/2014/5077
Studies on the effects of fresh shoot biomass of Tithonia diversifolia on the germination, growth performance and yield of cowpea (Vigna unguiculata L.) were carried out at the experimental site of the Department of plant science of Ekiti State University, Ado Ekiti in the 201...
Open access
Research Article10.9734/AJEA/2013/4361
Aims: To determine resistance rates and patterns of certain uropathogens, including E. coli, Klebsiella spp. and Pseudomonas spp., isolated from hospitalized urinary tract infections patients, to aminoglycoside antibiotics and to detect the most prevalent plasmid-mediated aminogl...
Open access
Research Article10.9734/BMRJ/2013/5167
Aims: Literature is calling the attention to several risks for developing prostate cancer (Pca), and race is one of them. We performed an analysis of data of the charts of all unfavorable PCa (uPCa) treated with the combination of high-dose-rate brachytherapy (HDR) and external b...
Open access
Research Article10.9734/BJMMR/2013/4892
With the fast development of computer and network technology, streaming media has attracted more and more attention. The concurrent capacity is a major performance index, especially for media service providers. In the current literature, the concurrent capacity of a server is usu...
Open access
Research Article10.9734/BJMCS/2013/5152
Aims: Vinasse that is bottom product of distillation unit from alcohol industry contains Chemical Organic Compound (COD) in high concentration. The purpose of this study was to investigate the effect of COD/N ratios of substrate and pH control to biogas production from vinasse. S...
Open access
Research Article10.9734/IJBCRR/2013/3797
Aims: The objective of the present study was to develop a bioadhesive bilayered buccal patch of Nimodipine (15 mg) using Eudragit Rs 100 as secondary layer and a primary layer with Hydroxy propyl methyl cellulose and Hydroxy propyl cellulose JF. Methodology: Bilayered buccal patc...
Open access
Research Article10.9734/BJPR/2013/5670
Aims: It is the intention of the authors to through this paper; evaluate the current situations in Nigeria by highlighting the recent reforms in the solid minerals sector and how these reforms can help sustain viable mineral exploration and mining activities. This study aim at in...
Open access
Research Article10.9734/BJAST/2014/3706
Background: Nosocomial infections have become a major challenge in health care delivery institutions, as they affect the quality of health care delivered. The medical imaging department is central within the hospital to the diagnosis of illness and disease; hence the need to inve...
Open access
Research Article10.9734/BJAST/2014/2336