Objective: The objectives of this study were to identify stable anhydrous emulsions via pseudo ternary phase diagram, optimize artemether-loaded batches using factorial design and subsequently evaluate the antimalarial activity. Methodology: Using labrasol®, triacetin® and laurog...
Open access
Research Article10.9734/BJPR/2014/5279
Aims: Oxcarbazepine was formulated as suspension in order to perk up the palatability, augment bioavailability of the product, furthermore extended to estimate good degree of in vitro in vivo correlation (IVIVC). Study Design: Formulation and Evaluation of Oxcarbazepine Suspensio...
Open access
Research Article10.9734/BJPR/2014/4763
Background: Information on economic burden of hypertension is needed for relevant decisions and policies due to escalating cost of disease management. Aims: The study assessed economic burden of pharmacotherapy in hypertension management on the National Health Insurance Scheme (N...
Open access
Research Article10.9734/BJPR/2014/3983
Aims: Stability indicating densitometry-TLC assay was established and validated for determination of azelastine hydrochloride (AZT) and emedastine difumarate (ETD) in the presence of their acid and oxidative degradants. Methodology: Forced degradation was performed using 30% H2O2...
Open access
Research Article10.9734/BJPR/2014/3693
In order to evaluate the synergistic action of essential oils (EO) on the antifungal activity of honey, a comparative method of adding honey with and without EO to culture media was used. One variety of honey and five EO types were used to determine the minimum inhibitory concent...
Open access
Research Article10.9734/BJPR/2014/5332
Aims: Misuse of antimicrobial medicines is a major contributory factor to development of resistant strains of micro-organisms, therapeutic failure and increased healthcare costs in many countries. To identify pattern of antimicrobial use among undergraduate students of the Univer...
Open access
Research Article10.9734/BJPR/2014/5972
Objective: To evaluate the role of anti-depressants (Duloxetine) and NSAID (Dexibuprofen) in a new rat model of chronic induced depression. Methods: Twenty four male wistar rats were divided into 4 groups of 6 animals each. Group I to IV served as vehicle control, osteoarthritis...
Open access
Research Article10.9734/BJPR/2014/4040
Aims: The leaves of Gmelina arborea (ROXB.) (Family Verbenaceae) are widely used in the folklore to treat various types of diseases. In this study, the antioxidant and cytotoxic activities of different methanolic extracts and the derived subfractions of 90% methanolic extract of...
Open access
Research Article10.9734/BJPR/2014/6018
Aims: Sequel to the resurgence of TB co-infection in HIV/AIDS patients in sub-Saharan Africa, efavirenz has become an important component of the highly active antiretroviral treatment (HAART). The objective of this study therefore is to provide a simple reversed-phase high perfor...
Open access
Research Article10.9734/BJPR/2014/4123
The correlation equation Dc,f,vapΨo = i + f *N have been used for the description of thermodynamic functions DΨo of free energy, heat, entropy and heat capacity of the combustion, formation and vaporization processes for alkanes of the different space structure. The i and f are s...
Open access
Research Article10.9734/ACSJ/2014/4844
Aim: To study the applicability of the solvatic retention model for the prediction of retention times in gradient elution of phenylisothiocyanate derivatives of natural amino acids. Methodology: The solvatic retention model of reversed-phase liquid chromatography has been used to...
Open access
Research Article10.9734/ACSJ/2014/6299
Aims: This study was performed to develop a fast and simple method for the quantitative analysis of Captopril in tablet powder by FT-Raman Spectroscopy and PLS regression. The effect of different preprocessing methods on multivariate calibration was studied. Methodology: Four dif...
Open access
Research Article10.9734/ACSJ/2014/6087
Activated carbons prepared from shea cake (CA-K) and cotton cake (CA-C) were investigated for removal of four dyes in aqueous solutions (0 – 200 mg/L): Reactive Black 5 (RB5), Methylene blue (BM), Reactive Orange 16 (RO16) and Methyl Orange (MO) from water by adsorption. The acti...
Open access
Research Article10.9734/ACSJ/2014/5403
Aims: Synthesis, characterization, antimicrobial-, antituberculosis-, and antitumor activity of a few 6,11-bisthiasteroidal analogues have been carried out. Methodology: Subsequent reaction of the mixture 3 with phenylhydrazine hydrochloride/hydrazine hydrochloride under reflux i...
Open access
Research Article10.9734/ACSJ/2014/6269
Self-evaluation is defined as learners judging the quality of their work, based on evidence and certain criteria, for the purpose of improvement. Self-evaluation consists of reassessment, and ensuring follow through of all required duties. The goal of self-evaluation is adaptatio...
Open access
Research Article10.9734/BJESBS/2014/5066