Value of Red Cell Distribution Width in Children with Congenital Heart Disease Associated- Pulmonary Arterial Hypertension
Hassnaa Atef Hassan, Rehab Elmeazawy, Hossam Hodeib, Doaa El Amrousy
Asian Journal of Pediatric Research · pp. 35–41 · Published 15 Jan 2024
10.9734/ajpr/2024/v14i1319Abstract
Background: Pulmonary arterial hypertension (PAH) commonly occurs as a consequence following untreated congenital heart disease (CHD). It’s often related to high morbidity and mortality rates. The work was aimed at assessing the RDW measurements in children who had PAH-CHD. Methods: Thirty children who have PAH-CHD took part in this study. Electrocardiography and echocardiographic evaluation were applied to all participants. RDW, a parameter included in complete blood count, was measured. Results: Our study involved thirty children. Up to 53.3% of them were males, whose age varied between three months and twelve months with median of 5 months. The optimal cutoff RDW measurement reached 17.0% (mean); a significant relation between RDW level and low oxygen saturation was reported (p=0.02), right ventricular fractional area change (p=0.023), and left ventricular ejection fraction (p=0.13). Conclusion: RDW, a parameter included in the standard complete blood count, showed a sagnificant elevation in children who had PAH-CHD children. In addition, it was significantly correlated with hypoxia and right ventricular fractional area change and left ventricular ejection fraction.
References (19)
- 1 Haemodynamic definitions and updated clinical classification of pulmonary hypertension [DOI]
- 2 Red cell distribution width in heart failure: Prediction of clinical events and relationship with markers of ineffective erythropoiesis, inflammation, renal function, and nutritional state [DOI]
- 3 Paediatric pulmonary arterial hypertension: updates on definition, classification, diagnostics and management [DOI]
- 4 Haemodynamic evaluation of pulmonary hypertension [DOI]
- 5 Persistent increase in red cell size distribution width after acute diseases: A biomarker of hypoxemia? [DOI]
- 6 Prognostic factors in pediatric pulmonary arterial hypertension: A systematic review and meta-analysis [DOI]
- 7 Heart rate responses during the 6-minute walk test in pulmonary arterial hypertension [DOI]
- 8 The prognostic value of various biomarkers in adults with pulmonary hypertension; a multi-biomarker approach [DOI]
- 9 Echocardiography for the Assessment of Pulmonary Hypertension and Congenital Heart Disease in the Young [DOI]
- 10 Pattern and Clinical Profile of Congenital Heart Disease in A Teaching Hospital [DOI]
- 11 Red blood cell distribution width as a related factor of pulmonary arterial hypertension in patients with systemic sclerosis [DOI]
- 12 Ambulatory respiratory rate trends identify patients at higher risk of worsening heart failure in implantable cardioverter defibrillator and biventricular device recipients: a novel ambulatory parameter to optimize heart failure management [DOI]
- 13 Unbiased Phenome-Wide Association Studies of Red Cell Distribution Width Identifies Key Associations with Pulmonary Hypertension [DOI]
- 14 Prognostic biomarkers in pediatric pulmonary arterial hypertension [DOI]
- 15 A low resting heart rate at diagnosis predicts favourable long-term outcome in pulmonary arterial and chronic thromboembolic pulmonary hypertension. A prospective observational study [DOI]
- 16 Usefulness of Red Cell Width Distribution (RDW) in the Assessment of Children with Pulmonary Arterial Hypertension (PAH) [DOI]
- 17 Hypoxemia in a Patient with Pulmonary Arterial Hypertension. Getting to the Heart of the Matter [DOI]
- 18 Congenital heart disease and pulmonary hypertension among Down syndrome pediatric patients [DOI]
- 19 Assessment of cross-sectional lung ventilation–perfusion imbalance in primary and passive pulmonary hypertension with automated V/Q SPECT [DOI]
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Xugang Tang, Lu-Xun Tang, Shuang Li · International Journal of General Medicine · 2026
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