Status of Some Antioxidant Micronutrient and Pregnancy Outcomes in Ghanaian Adolescents Attending Antenatal Clinic in Urban (Suntreso) and Rural (Mampong) Hospitals
Jessica Ayensu, Anthony Edusei, Ibok Oduro, Christopher Larbie
European Journal of Nutrition & Food Safety · pp. 120–127 · Published 19 Jul 2017
10.9734/EJNFS/2017/24209Abstract
Aims: Antioxidants are important in maintaining cellular function in normal pregnancy and are needed for mitigating the effects of oxidative stress. However, there is paucity of information on the importance of antioxidants in pregnant adolescents. This study was therefore aimed at assessing maternal antioxidant micronutrient status and its impact on pregnancy outcomes in Ghanaian pregnant adolescents. Study Design: Prospective Cohort study. Place and Duration of Study: Mampong and Suntreso Government hospitals in the Ashanti Region of Ghana between March and November 2014. Methodology: We included 100 pregnant adolescents aged 11 to 19 years. Two 24 hr recall sessions were used to assess dietary antioxidant micronutrient (Vitamin A, E, C, Zinc and Selenium) intakes of study participants. Biochemical status was assessed by measurement of serum Vitamin A, zinc and selenium using standardized methods. Pregnancy outcomes were obtained from hospital records after parturition. Results: The mean intakes of Vitamin A (246.86±26.80 mcg/d), E (7.32±0.46 mg/d) and zinc (7.56±0.42 mg/d) of participants during the study were below the RDA for the nutrients. The mean serum concentrations of Vitamin A (22.64±1.78 µg/dl) and zinc (137.43±25.27) were found to be higher than reference values. However, with a mean concentration of 63.20±13.58 µg/dl, serum selenium deficiency was observed in 74% of the participants. The mean birth weight and gestational age of the study population was 2.89±0.05 kg and 38.23±1.06 weeks, respectively (for 43 participants). Twenty-three percent (23%) of the babies were born with low birth weight. Further statistical analysis revealed no association between the antioxidant micronutrient status and birth weight and gestation age. Conclusion: No association was found between the antioxidant micronutrient status and pregnancy outcomes among Ghanaian pregnant adolescents. However, larger epidemiological studies and intervention trials are required to reinforce or refute the beneficial role of antioxidant micronutrient on pregnancy outcomes.
References (24)
- 1 Food and Agriculture Organization of the United Nations [DOI]
- 2 Role of oxidative stress in female reproduction [DOI]
- 3 Ghana Demographic and Health Survey 2008
- 4 The Importance of Antioxidant Micronutrients in Pregnancy [DOI]
- 5 West African Food Composition Table
- 6 Maternal selenium status during early gestation and risk for preterm birth [DOI]
- 7 Pregnant Adolescent and Adult Women have Similarly Low intakes of Selected Nutrients [DOI]
- 8 Reverse-Phase High-Performance Liquid Chromatography (HPLC) Analysis of Retinol and Retinyl Esters in Mouse Serum and Tissues [DOI]
- 9 Oxidative stress and inflammation in pregnancy [DOI]
- 10 Maternal Antioxidant Levels in Pregnancy and Risk of Preeclampsia and Small for Gestational Age Birth: A Systematic Review and Meta-Analysis [DOI]
- 11 Food and nutrient intakes by pregnant Nigerian adolescents during the third trimester [DOI]
- 12 Nutrient Inadequacy Is Prevalent in Pregnant Adolescents, and Prenatal Supplement Use May Not Fully Compensate for Dietary Deficiencies [DOI]
- 13 Selenium and preeclampsia: A global perspective [DOI]
- 14 Micronutrient Intakes from Food and Supplements in Australian Adolescents [DOI]
- 15 Effects of vitamin E supplementation on some pregnancy health indices: a randomized clinical trial [DOI]
- 16 Haptoglobin Phenotype, Preeclampsia Risk and the Efficacy of Vitamin C and E Supplementation to Prevent Preeclampsia in a Racially Diverse Population [DOI]
- 17 Controlled trial of zinc supplementation in Chilean pregnant adolescents [DOI]
- 18 Predictors of Healthy Birth Outcome in Adolescents: A Positive Deviance Approach [DOI]
- 19 Zinc Supplementation during Pregnancy: A Randomized Controlled Trial
- 20 Zinc in plasma and breast milk in adolescents and adults in pregnancy and pospartum: a cohort study in Uruguay. [DOI]
- 21 Vitamin A status in pregnant women in Iran in 2001 and its relationship with province and gestational age [DOI]
- 22 Pregnant adolescents in Guam consume diets low in calcium and other micronutrients [DOI]
- 23 International Journal of General Medicine [DOI]
- 24 Nutrition Throughout the Life Cycle [DOI]
Cited by 18
Linda Afriyie Gyimah, Reginald Adjetey Annan, Charles Apprey · PLOS ONE · 2021
Reginald Adjetey Annan, Linda Afriyie Gyimah, Charles Apprey · Journal of Nutritional Science · 2021
Antima Gupta, Satinder Kaur · Cereal-Based Food Products · 2023
Jessica Ayensu, Herman Lutterodt, Reginald Adjetey Annan · Food Science & Nutrition · 2019
Nafiseh Shokri-Mashhadi, Mehri Khoshhali, Motahar Heidari-Beni · Journal of Tropical Pediatrics · 2022
Linda Afriyie Gyimah, Reginald Adjetey Annan, Charles Apprey · Human Nutrition & Metabolism · 2021
Linda A. Gyimah, Reginald A. Annan, Charles Apprey · 2020
Reginald Adjetey Annan, Linda Afriyie Gyimah, Charles Apprey · PLOS ONE · 2021
Linda Afriyie Gyimah, Reginald Adjetey Annan, Charles Apprey · 2020
Jessica Ayensu, Christopher Larbie, Reginald Adjetey Annan · Journal of Nutrition and Metabolism · 2020
Showing 10 of 18 known citations — external sources report more than can currently be individually listed.
Related research
- Influence of Socio-demographic Factors on Adolescent’s Sexual and Reproductive Health and Behaviour — shares topic coverage
- HIV Disclosure in Children in a Tertiary Hospital in Southern Nigeria–Child’s Perspective — shares topic coverage
- Studies on Male Adolescent Health-Risk Behaviors in East Kassala Locality - Kassala State, Sudan — shares topic coverage
- Effects of Peer and Provider-Based Education Interventions on HIV/AIDS Knowledge and Behaviour-Risk among in-School Adolescents in Ebonyi State, Nigeria — shares topic coverage
- Knowledge and Perception of Teenage Pregnancy in a Semi-Urban Setting in Rivers State, Nigeria — shares topic coverage
Article metrics
Real usage data collected on this platform.
58
Page views
0
PDF downloads
15
Outbound clicks
18
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.