Aim: This study aimed to evaluate the mitigative role of Moringa oleifera leaf fractions against tenofovir/lamivudine/dolutegravir(TLD)-induced toxicities in the Canton-S Drosophila melanogaster. Study Design: This is an experimental study. Place and Duration of Study: This study...
Open access
Research Article10.9734/ejmp/2025/v36i41287
Aim: To evaluate the longevity and ameliorative activities of Moringa oleifera leaf (MOL) extract against some HAART drug-induced toxicities in Drosophila melanogaster. Materials and Methods: The research was conducted at the Drosophila laboratory, Africa Centre of Excellence in...
Open access
Research Article10.9734/jocamr/2020/v11i430194
Aim: The study was designed to investigate antioxidant, survivability, fecundity, and locomotor activity of Moringa oleifera leaf (MOL) extract in Drosophila melanogaster. Materials and Methods: The study was conducted at the Africa Centre of Excellence in phytomedicine Research...
Open access
Research Article10.9734/ejmp/2020/v31i1530322
Background/Objective: Dolutegravir-based highly active antiretroviral therapy (DTG-HAART) is the preferred regimen in the management of HIV/AIDS. However, the reproductive and oxidative stress toxicity of DTG-HAART is unknown. This study was designed to investigate the reproduct...
Open access
Research Article10.9734/jamps/2020/v22i630177
Objective: This study intended to evaluate the toxic effects of Efavirenz-based highly active antiretroviral therapy (EFVb-HAART) on some antioxidant parameters, and free radical generation in D. melanogaster. Materials and Methods: The study was carried out at the Centre of Exce...
Open access
Research Article10.9734/jamps/2020/v22i230158
Aims: This study was designed to evaluate the effects of Efavirenz-based highly active antiretroviral therapy (EFVb-HAART, Efavirenz/Lamivudine/Tenofovir) with emphasis on survival, longevity, climbing ability, and reproductive capacity in D. melanogaster. Methods: The experiment...
Open access
Research Article10.9734/jabb/2020/v23i130136
Background: This research was carried out to estimate the total phenolic and flavonoid contents, assayed the in-vitro antioxidant potential, and estimate the median inhibitory concentration (IC50) of the methanol root extract of Ximenia americana, Linn. Study Design: It was an ex...
Open access
Research Article10.9734/jabb/2021/v24i1230258
Aim: The study aimed at assessing the LD50, fecundity and locomotor effects of Ximenia americana L in Drosophila melanogaster. Study Design: The study was an experimental design. Place and Duration of Study: The study was done in the drosophila laboratory, Africa Centre of Excell...
Open access
Research Article10.9734/ajbgmb/2020/v5i230123