Temitope Tunji Odunitan

Computational Evaluation of Some Schiff-Bases of Phenylisocytosine as Potent Inhibitors of Plasmodium falciparum Transketolase in Anti-Malarial Drug Discovery

Opeyemi Emmanuel Atanda, Adeola Folasade Ehigie, Tawakalit Abimbola Adisa, Lamidi Waheed Babatunde Olaniyan, Temitope Tunji Odunitan, Olatomide Ayodeji Fadare, Mary Oyindamola Jesulade, Adedamola Onikepo Adesina & Leonard Ona Ehigie · International Journal of Biochemistry Research & Review · 2025

Background: The increasing prevalence of drug-resistant Plasmodium falciparum strains, particularly resistance to frontline therapies such as artemisinin and its derivatives, poses a significant challenge to malaria control and eradication efforts. This necessitates the developme...

Open access Research Article 10.9734/ijbcrr/2025/v34i41021

In-Silico Evaluation of Phenylisocytosine and Its Analogs as Potent Inhibitors of Plasmodium Falciparum Transketolase: A Strategic Approach in Anti-Malarial Drug Discovery

Opeyemi Emmanuel Atanda, Lamidi Waheed Babatunde Olaniyan, Olatomide Ayodeji Fadare, Adeola Folasade Ehigie, Tawakalit Abimbola Adisa, Temitope Tunji Odunitan, Oluwabunmi Temitope Alabi, Bukola Adeola Omonijo, Aloba Gideon Oluwaseun & Leonard Ona Ehigie · International Journal of Biochemistry Research & Review · 2024

Background: The rise of drug-resistant Plasmodium falciparum strains, particularly those resistant to artemisinin-based combination therapies (ACTs), underscores the urgent need for alternative antimalarial agents targeting novel biochemical pathways. Aim: This study investigates...

Open access Research Article 10.9734/ijbcrr/2024/v33i6941