Tatsuya Yokoyama

Genomic Analysis of Fungal Species No.11243 Mutant Strains Provides Insights into the Relationship between Mutations and High Productivity

Makoto Matsui, Tatsuya Yokoyama, Toshitaka Kumagai, Kaoru Nemoto, Goro Terai, Masayuki Machida, Takashi Shibata & Sachiyo Aburatani · Biotechnology Journal International · 2015

Aims: FR901469 is a novel antifungal antibiotic produced by fungal species No.11243. Although we have several FR901469 high-producing mutant strains, the mechanism of high productivity is unclear. This study aims to unravel the relationship between mutations and FR901469 producti...