Emerging Strategies in Antimicrobial Drug Discovery: A Review of Target-Based and Phenotypic Screening Approaches
Idrees Idrees Aliyu, Zephaniah Isaiah, Samson Tesfaye Gebre, Muhammad Mustapha, Muhammad Yusuf Abdulkadir, Alhassan Abdullahi Ndagi & Muhammad Kabir Usman · South Asian Journal of Research in Microbiology · 2026
Antimicrobial resistance has intensified the need for new chemical matter and new mechanisms of action, yet antibacterial discovery remains unusually vulnerable to attrition between a convincing molecular hypothesis and clinically relevant whole-cell activity. This critical narra...