Rafat M. Mohareb

Uses of 1-Cyanoacetyl-4-Phenyl-3-Thiosemicarbazide in the Synthesis of Antimicrobial and Antifungal Heterocyclic Compounds

Rafat M. Mohareb & Abeer A. Mohamed · International Research Journal of Pure and Applied Chemistry · 2012

The thiosemicarbazide synthesized from the reaction of cyanoacetylhydrazine phenylisothiocyanate reacted with acetoacetanilide gave the 2-pyridinone derivative 4. The reaction of the latter product with 1,3-dicarbonyl and α-halocarbonyl compounds gave the benzo[c]pyridine derivat...