Precious-Esther Ogechi Efuneshi

Redox-responsive Polymeric Nanocarriers for Controlled Anticancer Drug Delivery: A Critical Appraisal of Trigger Biology, Design Evidence and Translational Constraints

Riswat F. Musbau, Precious-Esther Ogechi Efuneshi, Ayomide Alao, Ronke Oluokun, Rafiu A. Raji, Theophilus Tolulope Fayinka & Malik O. Rabiu · International Journal of Biochemistry Research & Review · 2026

The difference in thiol concentration between the cytosol of tumour cells and the extracellular compartment has served for approximately two decades as the organising principle for a large family of polymeric nanocarriers designed to remain intact in circulation and to disassembl...

Open access Research Article 10.9734/ijbcrr/2026/v35i51155

From Pharmacophore to Free Energy: A Multi Scale Approach to DJ 1 (PARK7) Inhibitor Identification

Amena Khatun Manica, Ejoke Akatugba, Kesiena Loveth Eguono, Fisayo Wasilat Adeyemo, Precious-Esther Ogechi Efuneshi, Pruthvirajsinh Rajendrasinh Solanki, Dhruvilkumar Narendrakumar Patel, Bernard Opeyemi Adedeji, Abraham Olayeri, Adeyemi Ogunbowale, Joshua Temitope Adekeye & Idris Oladimeji Junaid · International Journal of Biochemistry Research & Review · 2025

DJ-1 (PARK7), a multifunctional protein implicated in both neurodegeneration and oncogenesis, remains an underexploited therapeutic target due to limitations in the structural and dynamic interrogation of its ligand-binding landscape. In this study, we employed an integrated comp...

Open access Research Article 10.9734/ijbcrr/2025/v34i61079