In Silico Screening of Rauwolfia Serpentina Phytochemicals as Orexin Receptor-2 Agonists for the Management of Narcolepsy
Pawan Yadav, Mohammad Azram, Mohd Faraz, Nadeem, Kashif Abbas, Mohd Mustafa, Mudassir Alam & Sarfaraz Khan · International Journal of Biochemistry Research & Review · 2025
The neuropeptide orexin/hypocretin plays a crucial role in numerous physiological processes such as regulation of sleep/wakefulness, appetite and emotions. Dysregulation of orexin signaling has been implicated in hypersomnia, especially in narcolepsy, characterized by excessive d...
Open access
Research Article
10.9734/ijbcrr/2025/v34i1951