P. O. Okonkwo

Survey of the Iron Status of Patients with Type 2 Diabetes Mellitus Attending Hospitals in Jos

P. O. Okonkwo & Z. S. C Okoye · International Journal of TROPICAL DISEASE & Health · 2014

Background and Objective: Epidemiological studies have shown that high body iron stores are associated with insulin resistance and type 2 diabetes. The aim of this study was to evaluate iron status of patients with type 2 diabetes mellitus (T2DM). Blood samples were collected fro...

Open access Research Article 10.9734/IJTDH/2014/10899

Comparative Effects of Antidiabetic Drug, Metformin and Deferoxamine, on the Hepatotoxic and Nephrotoxic Side Effects of Streptozotocin-induced Diabetes Mellitus in Rats

P. O. Okonkwo & Z. S. C. Okoye · Journal of Pharmaceutical Research International · 2014

Aims: The present study compared the effects of metformin (met) and deferoxamine (DFX) on the hepatotoxic and nephrotoxic side effects of streptozotocin experimental diabetes in rats using serum biochemical and histopathological indicators. Study Design: Following induction of di...

Open access Research Article 10.9734/BJPR/2014/11812

Comparative Effects of Antidiabetic Drug, Metformin and Deferoxamine, on Serum Lipids, Serum Ferritin and Endocrine Indicators of Diabetes Mellitus Complications in Sreptozotocin Diabetic Rats

P. O. Okonkwo & ZSC Okoye · International Journal of Biochemistry Research & Review · 2014

Aims: Increasing evidence has indicated that iron overload not only increases risks of insulin resistance and diabetes, but also causes cardiovascular diseases in non-diabetic and diabetic subjects. The present study compared the effects of metformin (met) and deferoxamine (DFX)...

Open access Research Article 10.9734/IJBCRR/2014/11811