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Osuvwe C. Orororo

Publications (8)

Cardio-hematoprotective Effects of Manihot esculenta and Vernonia amygdalina Leaf Extract against Phenylhydrazine-induced Hemolytic Anemia in Rats

Osuvwe C. Orororo, Oghenetekevwe Efekemo, Isioma C. Okonta, Gloria A. Oigbokie & Mordecai O. Oghene-udi · Asian Hematology Research Journal · 2026

Phenylhydrazine (PHZ)-induced hemolytic anemia is associated with oxidative stress and hematological dysfunction. This study evaluated the cardio-hematoprotective effects of combined Manihot esculenta and Vernonia amygdalina leaf extracts in PHZ-induced rats. Rats were divided in...

Open access Research Article 10.9734/ahrj/2026/v9i3255

Evaluation of Anti-Inflammatory and Analgesic Effects of Allophylus spicatus Leaf Extract in Mice

Osunu M. Idenyi, Osuvwe C. Orororo, Israel O. Efejene, Michael E. Aisuodionoe & Uboho F. Umoren · Journal of Complementary and Alternative Medical Research · 2024

This study examined the analgesic and anti-inflammatory activity of an ethanolic extract of Allophylus spicatus leaves in albino mice, taking into account the socioeconomic impacts of pain and inflammation as well as the need to search for effective antipain and anti-inflammatory...

Open access Research Article 10.9734/jocamr/2024/v25i9571

Evaluation of Genotoxicity by Comet Assay in Tissues of Clarias gariepinus Exposed to Cassava Effluent

Daniel I. Olorunfemi, Osuvwe C. Orororo, N. E., Iloduba, Ejovi Osioma, Enyohwo D. Kpomah & Ogheneovo L. Osio · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Untreated wastewater discharge into waterbodies poses a number of risks, including the potential for aquatic organisms' DNA to be damaged. Using the comet assay, this study assessed the genotoxic impact of cassava wastewater on the gonads, liver, and gills of post-juvenile Claria...

Open access Research Article 10.9734/ajbgmb/2024/v16i7394

Co-administration of Vitamin E and Quercetin Ameliorates Sodium Fluoride-induced Toxicities in Wistar Rats

Gabriel O. Ibobo, Divine A. Onobrudu, Osuvwe C. Orororo, Othuke B. Odeghe & Israel O. Efejene · Asian Journal of Research in Biochemistry · 2025

High dosages of fluoride have damaging effects on humans and animals. This study examined the beneficial role of co-administration of quercetin and vitamin E on sodium fluoride (NaF)-induced toxicities in Wistar rats because there are few documented reports on the synergistic eff...

Open access Research Article 10.9734/ajrb/2025/v15i3382

Assessment of Cardiovascular Function in Periodontitis and Diabetes Mellitus Induced Rats Treated with Black Seed (Nigella sativa) Oil

Abdulwasiu. A. Busari, Chidinma C. Obadiah, Osuvwe C. Orororo, Israel O. Efejene, Michael E. Aisuodionoe, Esthinsheen Osirim, Samantha DeLoache, Collins I. Ebu, Abdullahi A. Adejare & Kabir Badmos · Asian Journal of Cardiology Research · 2024

Diabetic periodontitis and diabetes worsen cardiovascular disease, which is a major cause of morbidity and death globally. Although Nigella sativa (NS) oil has anti-inflammatory, antioxidant, and hypoglycemic qualities, little is known about how well it can treat periodontitis an...

Open access Research Article 10.9734/ajcr/2024/v7i1224

Comparative Analysis of the Phytochemicals, Minerals, Antioxidant and Antimicrobial Activities of Aqueous and Ethanolic Extracts of Rauvolfia vomtoria Leafs

Divine A. Onobrudu, Chiamaka P. Nzebude & Osuvwe C. Orororo · Asian Plant Research Journal · 2024

In this study, the phytochemicals, B vitamins, minerals, antioxidants and antimicrobial activities of aqueous and ethanolic extracts of Rauvolfia vomtoria leaves were determined and compared. Qualitative and quantitative phytochemical analysis, mineral and B vitamin composition,...

Open access Research Article 10.9734/aprj/2024/v12i5271

Genotoxic Effects of Cassava Effluent on the Expression of Selected Genes in the African Catfish, Clarias gariepinus

Daniel I. Olorunfemi, Oghenekparobo Oteri, Osuvwe C. Orororo, Tina-Bayoko B. Enize, Charles Pere & Ejovi Osioma · Journal of Advances in Biology & Biotechnology · 2024

Aim: A cause for worry is the wastewater that is released into the environment or public sewers without any sort of purpose during the processing of Manihot esculenta Crantz. Fish and other aquatic species may suffer negative consequences if wastewater is discharged into streams...

Open access Research Article 10.9734/jabb/2024/v27i5794

Immunohistochemistry and Histology Evaluation of Neurodevelopmental and Neurocognitive Changes in the Offspring of Depressed Mice Administered Paroxetine Prenatally

Israel O. Efejene, Benneth Ben-Azu, Anthony T. Eduviere, Osuvwe C. Orororo, Meashack O. Ijomone, Mega O. Oyovwi, Michael E. Aisuodionoe & Abdulwasiu A. Busari · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Depression, a prevalent biopsychiatry disability leading to dysfunction behavioural abilities due to its symptomatic expression, is much more severe in gestational period affected both maternal and child’s health. Paroxetine, a selective serotonin reuptake inhibitors (SSRI) is us...

Open access Research Article 10.9734/ajrimps/2026/v15i1363