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Onoriode Andrew Udi

0000-0003-3690-5664

Publications (5)

Kelch-like ECH-associated Protein 1-nuclear Factor Erythroid 2-related Factor 2 Pathway Activation in Neuroprotection and Cognitive Enhancement

Onoriode Andrew Udi & Charles German Ikimi · International Neuropsychiatric Disease Journal · 2025

Neurodegenerative diseases and cognitive decline pose significant global health challenges. The Kelch-like ECH-associated protein 1 (Keap1) – nuclear factor erythroid 2-related factor 2 (Nrf2) pathway is a master regulator of cellular defense against oxidative stress and inflamma...

Open access Research Article 10.9734/indj/2025/v22i4500

Mitochondrial Dysfunction in Chlorpromazine (Induced) Neurodegeneration

Onoriode Andrew Udi, Udo Daniel EDEIFO & Charles German Ikimi · International Neuropsychiatric Disease Journal · 2025

Chlorpromazine CPZ, a widely used antipsychotic, has been linked to neurological side effects, including tardive dyskinesia, and evidence suggests a potential for long-term neurotoxic effects. This review synthesizes findings from in vitro and in vivo studies investigating the im...

Open access Research Article 10.9734/indj/2025/v22i3481

Alfavaca Aqueous Leaf Extract Protective and Ameliorative Effects on Lead Induced Hippocampus in Wistar Rats

Onoriode Andrew Udi, Trust Azubike Ijeomah, Lucky Omamuzo Ogagayere & Godswill Ogheneyebrorue Okoro · Asian Journal of Medicine and Health · 2023

There is a claim that using medicinal plants carelessly can be dangerous. The consequences of consuming numerous of these plants over time on the brain have remained a mystery. Alfavaca is one of such numerous herbs commonly used in Nigeria. This research was done to find out how...

Open access Research Article 10.9734/ajmah/2023/v21i11914

Mature Wistar Rats' Spleen and Liver Histomorphological Changes Related to the Duration of Atrazine Exposure

Praise Ajiri Odi, Onoriode Andrew Udi, Lilia Ebeye Chris-Ozoko & Mega Obukohwo Oyovwi · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2022

Background: Spleen and liver is secondary lymphoid organ that is highly sensitive to different chemicals. Widespread use of pesticides in agriculture has always been a matter of concern.  And surprisingly, atrazine distinguishes out for being used more frequently among numerous h...

Open access Research Article 10.9734/ajrimps/2022/v11i4204

Changes in Liver Histomorphology, Hematological Parameters and Lipid Profile of Cadmium-Exposed Rats Treated with Combined Leaf Extract of Vernonia amygdalina and Occimum gratissimum

Osuvwe Clement Orororo, Oghenekevwe Efekemo & Onoriode Andrew Udi · Asian Journal of Medicine and Health · 2022

Aim: This study was aimed at examing the effect of mixture of Ocimum gratissimum extract and Vernonia amygdalina extract on lipid profile and hematological parameters of Wistar rats administered with cadmium. Methodology: Sixteen female rats were divided into four groups and desi...

Open access Research Article 10.9734/ajmah/2022/v20i11759