A Computational Modeling Study on the Biomolecular Interactions of the Phytoconstituents of Nigella sativa with Anti-Apoptotic Proteins Mcl-1 and Bcl-x1
Olajumoke B. Oladapo, Toheeb A. Jumah, Justine U. Egbe, Jude O. Uzoechina, Aderonke E. Fakayode, Muhammad I. Adeyemi, Oluwaseyi P. Olaniyan, Chimunda A. Solomon, Zion O. Oluwasegun, Damilola M. Olatunde, Uche O. Arunsi, Samuel O. Olubode, Precious A. Akinnusi, Toheeb A Balogun & Sunday B. Akinde · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024
Cancer is the second leading cause of mortality worldwide. The strictly controlled physiological process of apoptosis is required for immune system function, maintenance of tissue homeostasis, and appropriate embryonic development. Anti-apoptotic proteins such as Bcl-xL and Mcl-1...