Skip to content
O

Oladele Ayobami Afolabi

Publications (3)

Effect of Curcumin on Cognitive Impairment in Aged Female Wistar Rats Subjected to Intestinal Ischemia-reperfusion Injury

Opeyemi Sodiq Hammed, Oladele Ayobami Afolabi, Richard Adedamola Ajike, Babatunde Adebola Alabi, Olubunmi Simeone Oyekunle, Waidi Adeoye Saka, Janet Oreoluwa Adedeji, Bamidele Oluwole Olusola & Olajumoke Deborah Ogunleye · Journal of Applied Life Sciences International · 2025

Cognitive deficit, more common with age, it affects memory and cognitive functions. Intestinal ischemia-reperfusion injury (IIRI) causes systemic inflammation that can damage the brain, particularly the hippocampus. Curcumin, an active ingredient found in turmeric have neuroprote...

Open access Research Article 10.9734/jalsi/2025/v28i1676

Timed Administration of Febuxostat Improved Testicular Function Following Testicular Ischemia-reperfusion Injury Via Inhibition of MDA/NO Pathway, Down-regulation of Toll-like Receptor 4 Expression and Restoration of Reproductive Hormones

Oreoluwa Janet Adedeji, Oladele Ayobami Afolabi, Richard Adedamola Ajike, Olubunmi Simeone Oyekunle, Waidi Adeoye Saka, Olajumoke Deborah Ogunleye, Bamidele Oluwole Olusola, Oluwaseun Samuel Hezekiah, Sodiq Opeyemi Hammed & Babatunde Adebola Alabi · Journal of Advances in Biology & Biotechnology · 2024

Introduction: Testicular ischemia-reperfusion injury (TIRI) generates reactive oxygen species (ROS) through xanthine oxidase (XO) activity in the ischemic phase and leukocyte infiltration to the site of injury during reperfusion leading to oxidative stress, inflammation, and disr...

Open access Research Article 10.9734/jabb/2024/v27i121800

Sequential Administration of Febuxostat, Amlodipine and Vitamin E Attenuate Oxidative Stress and Improve Spermatogenesis in Testicular Ischemia Reperfusion Injury in Wistar Rats

Richard Adedamola Ajike, Oladele Ayobami Afolabi, Ayodeji Folorunsho Ajayi, Olajumoke Deborah Ogunleye, Waidi Adeoye Saka, Olusola Bamidele & Oluwaseun Samuel Hezekiah · International Journal of Biochemistry Research & Review · 2024

This study investigated the effects of sequential administration of febuxostat, amlodipine, and vitamin E on oxidative stress and spermatogenesis following testicular ischemia-reperfusion injury (TIRI) in Wistar rats. Ninety male rats (120-150 g) were divided into 9 groups (n=10...

Open access Research Article 10.9734/ijbcrr/2024/v33i6894