Ogbonna Chidera Gloria

Phytochemical Screening and Ameliorative Potential of Ethyl Acetate Fraction of Polyaltha logifolia Leaves on Croton Oil-induced Hemorrhoid in Albino Wistar Rats

Ugwu Obiora Celestine, Umeakuana Chidinma Doris, Ogbonna Chidera Gloria, Uzoefuna Chima Casmir, Onyima Glory Chinemerem, Adonu Cyril Chekwube, Asogwa Felix Keneolisa, Omeh, Chijioke Romanus, Idokoja Levi Onyebuchi, Offia Ogbonna Raymond, Onah Benjamin Emenike, Pete Princess Oluchukwu & Anosike Chioma Assumpta · International Journal of Biochemistry Research & Review · 2025

Background: Hemorrhoids are a very common anorectal condition defined as the symptomatic enlargement and distal displacement of the normal anal cushions. Aim: The research is aimed at investigating the ameliorative potential of ethyl acetate fraction of Polyaltha logifolia leaves...

Open access Research Article 10.9734/ijbcrr/2025/v34i2959

Assessment of the Potential Mechanisms of Anti-diarrhoeal Activities of Ethanol Extract of Monoon longifolium Leave in Wistar Rat

Ugwu Obiora Celestine, Umeakuana Chidinma Doris, Ogbonna Chidera Gloria, Asadu Chidinma Lilian, Ali Ibeabuchi Jude, Asogwa Felix Keneolisa, Uzoefuna Chima Casmir, Ogbu Chukwudi Collins, Nwokedi Chukwuebuka Kingsley & Anosike Chioma Assumpta · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

Background: Numerous diseases related to diarrhea are the primary cause of morbidity and mortality in underdeveloped countries, accounting for hundreds of thousands of deaths annually. Polyalthia longifolia, the false ashoka, commonly referred to as Monoon longifolium is a tree s...

Open access Research Article 10.9734/jamps/2024/v26i9713

Anti-inflammatory Effect of Musa acuminata Sap Derived Flavonoids on a Carrageenan Induced Inflammatory Model in Wistar Rats

UzoefunaCasmir Chima, Ani Celestine Okafor, Chinedu Happiness Uzoagulu, Uzoigwe Jide Uzowulu, Nwokedi Anslem Kenechukwu, Ogbonna Chidera Gloria & Nweke Maduka Luke · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Background: Inflammation is a protective physiological response to harmful stimuli, but excessive inflammation can contribute to tissue damage and disease. Conventional anti-inflammatory drugs are effective but may produce adverse effects with prolonged use. Flavonoids from plant...

Open access Research Article 10.9734/jamps/2026/v28i6865

Evaluation of the Anti-inflammatory Effects of Methanol Extract of Rauwofia vomitera Leaves (MERVL) Using In-vivo Based Assays

Ugwu Obiora Celestine, Ukpabi-Ugo Chigozie Jacinta, Asadu Chidinma Lilian, Ali Ibeabuchi Jude, Asogwa Felix Keneolisa, Ugodi Gerald Walter, Obasi Uchenna Emmanuel, Ogbonna Chidera Gloria, Nwokedi Chukwuebuka Kingsley & Anosike Chioma Assumpta · International Journal of Biochemistry Research & Review · 2024

Background of the Study: The response of the body to harmful stimuli, such as tissue damage or a pathogenic infection is known as inflammation.  Rauwofia vomitera is a medicinal plant that is native to large areas of tropical Africa and it belongs to the family of Apocynaceae. It...

Open access Research Article 10.9734/ijbcrr/2024/v33i5877