Obinwa Benedict Nzube

Hepatoprotective Effects of Solanum macrocarpon Leaf Extract against Paraquat-induced Liver Toxicity in Wistar Rats

Uzozie Chikere Ofoego, Nwachukwu Chinecherem Favour, Obinwa Benedict Nzube, Ekwujuru Ezinne Uchechi, Ofoego Amarachukwu Ndubuisi & Ezeagu Darlington Kenechukwu · Journal of Advances in Medicine and Medical Research · 2025

Solanum macrocarpon is a nutrient-rich plant, while Paraquat is a widely used contact herbicide and has been linked to liver damage. This study evaluated the hepatoprotective effects of ethanolic leaf extract of Solanum macrocarpon (ELESM) against paraquat-induced liver toxicity...

Open access Research Article 10.9734/jammr/2025/v37i35763

Evaluating the Effect of Chloroform Inhalation as a Method of Euthanasia on the Cerebellum and Hippocampus of Adult Wistar Rats

Ugochukwu Samuel Aguwa, Okeke Somadina Nnamdi, Ezejindu Darmian Nnabuihe, Eze Chinyere Elizabeth, Azurunwa Ogechi, Obinwa Benedict Nzube, Ovie Ogbo. Felix, Obi Kelvin Chukwuemeka, Onwuelingo Sopuru, Okonkwo David, Doris Ogbuokiri & Okeke Chijioke · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Chloroform inhalation is a common method of rodent euthanasia in Nigeria for research purposes. This work is designed to evaluate the consequence of this method of sacrifice on the cerebellum and hippocampus of Wistar rats. Twenty male Wistar rats weighing between 160 and 180 wer...

Open access Research Article 10.9734/jamps/2020/v22i630176