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O. D. Omotoso

Publications (16)

Assessment of the effect of Watermelon and Aloe Vera on Cadmium Induced Heart Damage in Adult Wistar Rats (Rattus novergicus)

O. D. Omotoso, S. A. Adelakun, H. B. Akpan, U. A. Yusuf, O. O. Adeleye & O. O. Adeyinka · Cardiology and Angiology: An International Journal · 2016

The aim of the study was to investigate the antioxidant property of watermelon and aloe vera against cadmium damaging effect on the heart and the packed cell volume of the blood. Thirty five Wistar rats were obtained and acclimatized for two weeks. They were randomly divided into...

Open access Research Article 10.9734/CA/2016/24272

Assessment of the Effects of Moringa oleifera Oil, Anacardium occidentale Oil and Vitamin C and E on the Reticular Fibres of Cadmium- Induced Liver Damage in Wistar Rats

O. D. Omotoso, S. A. Adelakun, U. A. Yusuf, O. O. Adeleye & O. O. Adeyinka · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Background: Cadmium is one of the most toxic pollutants in the environment. This study aims at assessment of the effects of Moringa oleifera oil, Anacardium occidentale oil and vitamin C and E on the reticular fibres of cadmium- induced liver damage in wistar rats. Methods: Thirt...

Open access Research Article 10.9734/JAMPS/2016/24239

PAS Exfoliation in Watermelon and Aloe Vera Recuperate Glycogen in Heart Tissue Damaged by Cadmium in Adult Wistar Rats (Rattus novergicus)

O. D. Omotoso, S. A. Adelakun, N. O. Amedu, U. P. Idoko, I. S. Oji & H. B. Akpan · Cardiology and Angiology: An International Journal · 2016

Cadmium (Cd) is a major concern of World Health Organization for public health and is a highly toxic element which is naturally present in all parts of the environment. Watermelon contributes nutritional agents as antioxidants and some specific amino acid. Aloe vera plants contai...

Open access Research Article 10.9734/CA/2016/24273

Antioxidant Properties of Moringa oleifera Oil and Anacardium occidentale Oil on Cadmium Induced Liver Damage in Adult Wistar Rats

O. D. Omotoso, S. A. Adelakun, N. O. Amedu & U. P. Idoko · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Cadmium (Cd) is one of the most toxic heavy metals found in the environment. This study aimed at combined effects of Moringa oleifera (Mo) oil and Cashew nut oil on cadmium-induced liver damage in wistar rats. Thirty-five wistar rats of both sexes were randomly divided into seven...

Open access Research Article 10.9734/JAMPS/2016/24250

Ameliorative Effects of Watermelon and Aloe vera against Cadmium Damage on the Histomorphology of the Heart Tissue of Adult Wistar Rats (Rattus novergicus)

O. D. Omotoso, S. A. Adelakun, N. O. Amedu, U. P. Idoko, I. S. Oji & H. B. Akpan · Cardiology and Angiology: An International Journal · 2016

Cadmium (Cd) is a toxic element that can produce reactive oxygen species. Fruits and vegetables are natural sources of various bioactive compounds. Watermelon contains nutritional agents like lycopene, citrulline and arginine and Aloe vera is used for therapeutic purposes. This s...

Open access Research Article 10.9734/CA/2016/24276

Moringa Leaf Extract Ameliorates Cerebral Cortex Tissue Damage in STZ-Induced Diabetes Condition

O. D. Omotoso, V. O. Olawuyi, J. O. Owolabi & B. J. Dare · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Moringa oleifera is a plant that has huge nutritional and phytomedicinal values particularly due to its rich nutrients, antioxidants and medicinal phytochemicals. This investigation examined the effect of Moringa oleifera leaf extract on the histology of the prefrontal cortex of...

Open access Research Article 10.9734/JAMPS/2016/15989

Histological and Histochemical Evaluation of Anticadmium Toxicity Effects of Moringa oleifera Seed Oil and Anacardium occidentale Nut Oil in the Hippocampus of Juvenile Male Wistar Rats

O. D. Omotoso, J. O. Owolabi, Y. J. Samanja, B. J. Dare, E. A. Ashamu & S. A. Adelakun · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

The hippocampus is a part of the brain involved in memory formation, organization and storage; being a limbic system structure that is particularly important in forming new memories and connecting emotions and senses, such as smell and sound, to memories. Cadmium on the other han...

Open access Research Article 10.9734/JAMPS/2016/16035

Positive Anti-Cadmium Poisoning Anti-Oxidant Effects of Moringa Seed Oil and Cashew Nut Oil in Juvenile Wistar Rats Hippocampus

O. D. Omotoso, J. O. Owolabi, H. B. Akpan, B. J. Dare, E. A. Ashamu & S. A. Adelakun · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Moringa oleifera seed oil and Anacardium occidentale oil contain certain antioxidants including ascorbic acid, phenolics, flavonoids and carotenoids; these antioxidants have potentials to act against oxidative stress generated by cadmium accumulation and activities in tissues. Th...

Open access Research Article 10.9734/JAMPS/2016/16310

Histo-morphological Effects of Carica papaya on Cadmium Induced Prefrontal-Cortex Damage in Adult Wistar Rats

H. B. Akpan, O. D. Omotoso, E. Ogbonna, M. N. Negedu, S. A. Adelakun, F. E. Oladipupo, A. O. Adedeji, A. A. Akande, A. R. Olapade & P. K. Orisadiran · European Journal of Medicinal Plants · 2018

Background: This research investigated the recuperative (restorative) effect of aqueous extract of Carica papaya fruit on cadmium induced prefrontal-cortex damaged in adult Wistar rats (Rattus norvegicus). Previous research reports have confirmed that cadmium toxicity results in...

Open access Research Article 10.9734/EJMP/2018/16429

Antioxidant Properties of Carica papaya on Cadmium Toxicity on Prefrontal-Cortex of Adult Wistar Rats

H. B. Akpan, O. D. Omotoso, A. R. Olapade, E. Ogbonna, M. N. Negedu, A. A. Akande, A. O. Adedeji, F. E. Oladipupo & P. K. Orisadiran · European Journal of Medicinal Plants · 2018

Background: Cadmium is a carcinogenic agent in humans, and therefore, a cancer causing substance. In the body it is extensively circulated, but it is bound mainly to erythrocytes. Though cadmium binds to various macromolecules and proteins in the body, it is not well metabolized....

Open access Research Article 10.9734/EJMP/2018/22753

Recuperative Action of Aqueous Carica papaya Extract on Cadmium Induced Loss of Nissl Bodies in the Frontal Cortex

H. B. Akpan, O. D. Omotoso, E. Ogbonna, S. A. Adelakun, F. E. Oladipupo, A. A. Akande, P. K. Orisadiran & A. R. Olapade · Journal of Applied Life Sciences International · 2017

Background: Cadmium is a heavy metal that causes generation of free radicals that have been discovered to cause damage to cells and tissues in the body. This research work examined the damaging effects of cadmium, and the recuperative effect of Carica papaya aqueous extract to re...

Open access Research Article 10.9734/JALSI/2017/16430

Evaluation of Toxicological Effects of Oral Administration of Cadmium Nitrate on Liver of Adult Wistar Rats

S. A. Adelakun, O. D. Omotoso, U. A. Yusuf, O. O. Adeleye & O. O. Adeyinka · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Available evidence suggest that adverse effect of health are caused by heavy metal and cadmium nitrate(CdN) has been shown to cause adverse health effect worldwide and liver is one of the organs mostly affected. The present study evaluates toxic effects of cadmium nitrate on live...

Open access Research Article 10.9734/JAMPS/2016/23349

Herbology, Antibacterial and Antihaemorrhagic Effect of Allium sativum Linn (Lilliaceae) Extracts against Bacterial Meningitis Pathogens

Kokori Bajeh Tijani, Abdullahi Attah Alfa, O. D. Omotoso, Yahaya Junaidu & Umar Sabdat Unoyiza · Asian Journal of Advanced Research and Reports · 2021

Bacterial Meningitis pathogen (BMP) causes cellular hemorrhagic sepsis, metabolic, endocrine and neurologic disorders in human systems. This burden of the disease is highest in the developing countries and especially in the immunity compromised rural populations in Sub-Saharan Af...

Open access Research Article 10.9734/ajarr/2021/v15i130353

Nutritional Values and Medicinal Health Aspects of Brown, Brown-Black and White Cowpea (Vigna unguiculata L. Walp.) Grown in Okene, Kogi State, Nigeria

Abdullahi Attah Alfa, Kokori Bajeh Tijani, O. D. Omotoso, Yahaya Junaidu & Abullahi Aminu Sezor · Asian Journal of Advanced Research and Reports · 2020

Cowpea (Vigna unguiculata) is an annual legume thought to have originated in Nigeria. Cowpea has high protein and carbohydrate content with a relatively low fat content and a complementary amino acid pattern to that of cereal grains make it an important nutritional staple food in...

Open access Research Article 10.9734/ajarr/2020/v14i430348

Histomorphological Study of Effects of Oral Administration of Cadmium Nitrate on Heart of Adult Wistar Rats

S. A. Adelakun, O. O. Oyewo, O. D. Omotoso, N. O. Amedu & U. P. Idoko · Cardiology and Angiology: An International Journal · 2016

Cadmium nitrate occurs as a colorless solid. It is soluble in dilute acids and ethanol, acetone, water, diethyl ether, and ethyl acetate. This study examined the effects of Oral Administration of cadmium nitrate on histomorphology of the heart of adult wistar rats. Twenty (n=20)...

Open access Research Article 10.9734/CA/2016/24353

Lime Juice Induces Ovarian Follicle Degeneration and Reduces Serum Gonadotrophin Level in Rats Model

B. J. Dare, O. Beremako, O. D. Omotoso, O. T. Olaniyan, M. O. Shafe & S. C. Ifeonu · International STD Research & Reviews · 2015

Background: Lime juice possesses antimicrobial and anti-proliferative property and caused reduced sperm motility in animals. This study aimed at investigating the anti-proliferative effect of lime juice on the ovarian cortex of adult Wistar rats. Methods: Twenty (20) adult Female...

Open access Research Article 10.9734/ISRR/2015/8709