Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss, significantly impacting millions worldwide. The accumulation of amyloid-β (Aβ) plaques in the brain is a central feature of AD pathology, making it a key targe...
Open access
Research Article10.9734/indj/2025/v22i3480
Alzheimer's disease is a progressive neurological disorder that primarily affects older adults and is the most common cause of dementia. It involves the degeneration of brain cells, leading to memory loss, cognitive decline, and changes in behavior and personality. Worldwide, an...
Open access
Research Article10.9734/indj/2025/v22i3476
Nikita Gupta, Mohd Naveed Khan, Varda Farooqui, Guntoju Poojitha & Thipparam Kavya·Asian Journal of Immunology·2024
Vadadustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, may offer an oral alternative to injectable erythropoiesis-stimulating agents (ESAs) to treat anemia in patients undergoing peritoneal dialysis. Current standard of care for anemia linked to chronic kidney disea...
Open access
Research Article10.9734/aji/2024/v7i1153
Renal sympathetic denervation (RSDN) is a minimally invasive endovascular catheter treatment that treats resistant hypertension (high blood pressure that cannot be brought under control with medicines) by employing radiofrequency ablation or ultrasound ablation. Using radiofreque...
Rheumatoid arthritis (RA) is characterized by systemic synovitis, which destroys joints. With the discovery of biological disease-modifying anti-rheumatic medicines (bDMARDs) and the combination of traditional DMARDs, clinical remission is now seen as a reasonable and achievable...
Open access
Research Article10.9734/aji/2024/v7i1137
Urinary Tract Infections (UTIs) are some of the most common bacterial infections. Urinary Tract Infections are categorized into uncomplicated and complicated. Urinary Tract Infections are symptomatic when there are clinical urinary symptoms that indicate infection such as micturi...
The term “In vitro maturation” (IVM) describes the various stages of immature oocyte maturation in culture. The process of in vitro maturation (IVM) involves the collection of immature oocytes from antral follicles using an altered version of in vitro fertilization (IVF), wherein...
Open access
Research Article10.9734/arjgo/2024/v7i1226
The development of antibody-drug conjugates (ADCs) has significantly impacted cancer therapy, progressing from foundational discoveries in the late 19th century to contemporary clinical applications. With the approval of the first ADC in 2000 and subsequent advancements, includin...
Open access
Research Article10.9734/jcti/2024/v14i3259
Nikita Gupta, Sana Begum, Varda Farooqui, Summaiya Afreen & Pranitha Avunoori·Asian Journal of Immunology·2024
Iguratimod is a small novel compound considered as a disease-modifying anti-rheumatic drug (DMARD), which exhibits anti-inflammatory and immunomodulatory effects. Iguratimod acts directly on B cells by inhibiting the production of inflammatory cytokines (tumor necrosis factor-α,...
Open access
Research Article10.9734/aji/2024/v7i1132
Nikita Gupta, Swetha Singarapu, Hema Pasupuleti, Mohd Ilham Ahmed & Sameera Fatima·Asian Journal of Immunology·2023
Ankylosing spondylitis, also called spine osteoarthritis, radiographic axial spondyloarthritis is a form of arthritis which is autoimmune in nature and leads to chronic spine inflammation including inflammation of the sacroiliac joint (situated in between the base of the vertebra...