Nighat Sultana

Triterpenes and Triterpenoids Clinically Useful with Multiple Targets in Cancer, Malaria and More Treatment: Focus on Potential Therapeutic Value

Nighat Sultana · International Journal of Biochemistry Research & Review · 2017

Triterpenoids are the most promising plant secondary metabolites. Several triterpenoids, including ursolic acid, oleanolic acid, betulinic acid, celastrol, pristimerin, lupeol and avicins are representative group of phytochemicals possesses biological properties. Anti-tumor, anti...

Open access Research Article 10.9734/IJBCRR/2017/31165

(1H-Pyrrolo [2,3-b]pyridine)7-Azaindole Derivatives and Their Antiurease, Phosphodiesterase and β-glucuronidase Activity

Zafar S. Saify, Nighat Sultana, Ajmal Khan & Shazia Haider · International Journal of Biochemistry Research & Review · 2015

A variety of 7-azaindole analogs 1-14 with variable substituents on phenyl ring of phenacyl moiety were synthesized and evaluate for their urease, phosphodiesterase and b-glucuronidase Inhibitory potential. Compound 9 (IC50 = 2.19±0.37µM) showed potent urease inhibitory potential...

Open access Research Article 10.9734/IJBCRR/2015/10575

(1H-Pyrrolo [2,3-B] Pyridine) 7-Azaindole as Cholinesterase/ Glycation Inhibitors

Zafar Saied Saify, Nighat Sultana, Nousheen Mushtaq & Nazia Zaheer Ul Hasan · International Journal of Biochemistry Research & Review · 2014

As a part of our program to discover novel analoges of (1H-pyrrolo [2,3-b] pyridine) 7-azaindole having useful biological activities, a variety of 7-azaindole analogs 1-9 with variable substituents on phenyl ring of phenacyl moiety were synthesized and evaluated for their AChE, B...

Open access Research Article 10.9734/IJBCRR/2014/9721