Mohammed Hadi Al–Douh, Elham Abdalrahem Bin Selim, Hassan Hadi Abdallah, Hewa Y. Abdullah, Aisha Khalid Al–Bakri, Dahab Salim Al–Nohey, Samia Mabrook Bin Mahram, Khulood Mahfoudh Yusr & Faten Abdulaziz Bin Hawiel·Asian Journal of Applied Chemistry Research·2021
In this study, the computerized molecular docking method was used to investigate the interactions of five nitro diazo dye derivatives 1-5 with COVID-19, CLpro, RAF and PLpro as very important viral proteins to target the coronavirus SARS-CoV-2. Among the used diazo dyes, compound...
Open access
Research Article10.9734/ajacr/2021/v8i230187
Mohammed Hadi Al–Douh, Elham Abdalrahem Bin Selim, Edrees Muhammad Tahir, Sabah Ahmed Abdo Esmail, Yaman Ahmed Naji & Hassan Hadi Abdullah·Asian Journal of Applied Chemistry Research·2019
The biophysical interactions between the human serum albumin HSA and three synthesized diazo dyes 1-3 have been investigated by thermodynamic parameters and molecular docking technique. The binding constants Kb were calculated and the compounds were ranked according to their dock...
Open access
Research Article10.9734/ajacr/2019/v4i330113
Three new amide compounds 6, 8 and 9 were derived from diazo dye 4. 4-Hydroxy-3-methoxy-5-(2,6-dinitrophenyl) benzaldehyde 4 was reacted separately with compounds 5 and 7 to obtain 6 and 8, respectively. The amide compound 9 was synthesized by two different methods. The reaction...
Open access
Research Article10.9734/ajacr/2022/v11i230250
Two bis-Schiff Bases 1 and 2 are ligands that can coordinate with manganese metal to form stable complexes and have biological activity. Thermodynamic parameters, HOMO-LUMO energy levels and FTIR spectra of two ligands have been computed using B3LYP/6-311++G(d,p) functional of th...
Open access
Research Article10.9734/ajacr/2021/v10i230231
Elham Abdalrahem Bin Selim, Mohammed Hadi Al–Douh, Dahab Salim Al–Nohey, Wedad Mohammed Al–Haik & Khalid Saeed Sonbol·Asian Journal of Chemical Sciences·2020
Two Schiff base tetradentate ligands 4 and 5 were synthesized by condensation reactions of 4-hydroxy-3-methoxy-5-((2-nitrophenyl)diazenyl) benzaldehyde 1 with 1,2-diaminoethane 2 and 1,2-diaminobenzene 3, respectively. Treatment of synthesized ligands with the manganese (II) chlo...
Open access
Research Article10.9734/ajocs/2020/v7i419030
Unusual effects of intramolecular hydrogen bonds and dipole interactions are investigated using FTIR, NMR and X-Ray crystallography analyses of some imines. These phenomena affect both FTIR absorptions and chemical shifts.
Open access
Research Article10.9734/ajacr/2019/v3i330096