Evaluating the Effect of Iron (II) Chloride Induced Oxidative Stress in SH-SY5Y Cells and Its Role in Upregulation of α-Synuclein Expression
Mohammed Abba Dige & Emmanuel Paul Okoi · International Journal of Biochemistry Research & Review · 2019
The α-synuclein (SNCA) gene is a pathogenic gene identified in rare familial Parkinson Disease (PD). Recent studies highlight the role of DNA methylation in the pathogenesis of familial and sporadic PD. Hypomethylation in SNCA gene has been associated with increased SNCA gene exp...
Open access
Research Article
10.9734/ijbcrr/2019/v28i330148