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Michael Zimmermann

Publications (8)

Refinements to Assessment of Iodine Nutrition

Kevin Sullivan, Michael Zimmermann, Jonathan Gorstein, Gregory Gerasimov, Arnold Timmer & Juliawati Untoro · European Journal of Nutrition & Food Safety · 2015

Objectives: The main target groups of iodine programs are pregnant women (PW) and non-pregnant women of reproductive age (NPW), yet surveys frequently focus on school age children (SAC). It is unclear whether median urinary iodine concentration (mUIC) in SAC can be used as a surr...

Open access Research Article 10.9734/EJNFS/2015/21027

Serum and Dried Blood Spot Thyroglobulin as a Functional Biomarker of Iodine Status during Pregnancy

Sara Stinca, Maria Andersson, Juergen Erhardt & Michael Zimmermann · European Journal of Nutrition & Food Safety · 2015

Objectives: Thyroglobulin (Tg) is a sensitive marker for iodine deficiency and excess in school-aged children. DBS-Tg may be a promising functional biomarker also during pregnancy. Our objectives were to develop a new Tg assay and to determine if trimester-specific reference rang...

Open access Research Article 10.9734/EJNFS/2015/21253

Strategies to Enhance Iron Absorption from Tef-injera in Young Women

Maren Fischer, Ines Egli, Isabelle Aeberli, Michael Zimmermann & Richard Hurrell · European Journal of Nutrition & Food Safety · 2015

Objectives: Tef is a cereal indigenous to Ethiopia. The flour obtained is mostly used to produce a soft, pancake-like sourdough-bread, called injera. Since it contains considerable amounts of phytate, iron bioavailability from this Ethiopian staple is believed to be limited. We i...

Open access Research Article 10.9734/EJNFS/2015/21304

In Overweight Women, Adiposity-related Inflammation and Serum Hepcidin are Increased, Dietary Iron Bioavailability is decreased and Ascorbic Acid has Only a Negligible Enhancing Effect on Iron Bioavailability

Ana Carla Cepeda-Lopez, Sophia Wussler, Alida Melse-Boonstra, Michael Zimmermann & Isabelle Aeberli · European Journal of Nutrition & Food Safety · 2015

Objectives: Many countries are struggling with the double burden of malnutrition. Iron deficiency is prevalent in overweight and obese (OW/OB) subjects, likely due to adiposity-related inflammation increased hepcidin and decreased iron absorption. Because hepcidin reduces iron ef...

Open access Research Article 10.9734/EJNFS/2015/21333

Maternal Thyroid Function and Birth Outcomes after Iodine Supplementation in Mild-to-moderately Iodine-deficient Pregnant Women in Thailand

Sueppong Gowachirapant, Alida Melse-Boonstra, Pattanee Winichagoon, Ratanaporn Pornkul & Michael Zimmermann · European Journal of Nutrition & Food Safety · 2015

Objectives: To evaluate the effects of iodine supplementation in mild-to-moderately iodine-deficient pregnant Thai women on maternal thyroid function and birth outcomes. Methods: An RCT with 200 µg KI per day was conducted among 514 mild-to-moderately iodine-deficient pregnant Th...

Open access Research Article 10.9734/EJNFS/2015/21023

Using Stable Iron Isotopic Techniques and Serum Hepcidin Profiles to Optimize Iron Supplementation for Correction of Iron Deficiency in Young Women

Diego Moretti, Jeroen Goede, Markus Jiskra, Alida Melse, Swinkels Dorine, Tjalsma Harold & Michael Zimmermann · European Journal of Nutrition & Food Safety · 2015

Objectives: Determine the duration and magnitude of the serum hepcidin (sHep) rise induced by oral iron (Fe) supplements from single and consecutive-day Fe doses and measure bioavailability in healthy subjects. Methods: Twenty six subjects (serum ferritin, SF <20 µg/L) were ra...

Open access Research Article 10.9734/EJNFS/2015/21111

Evaluation of Zinc Bioavailability in Humans from Foliar Zinc Biofortified Wheat and from Intrinsic vs. Extrinsic Zn Labels in Biofortified Wheat

Coralie Signorell, Diego Moretti, Christophe Zeder, Fabian Tay, Erick Boy, Neelam Khetarpaul, Ismail Cakmak & Michael Zimmermann · European Journal of Nutrition & Food Safety · 2015

Objectives: Zinc biofortification may be a sustainable way to improve Zn status, but questions remain on Zn bioavailability. We produced a novel biofortified wheat by Zn foliar application, and a separate wheat cultivar was intrinsically labeled with a Zn stable isotope. Goals we...

Open access Research Article 10.9734/EJNFS/2015/21133

Effects of High and Low Dose Iron-Containing Micronutrient Powders for In-Home Fortification of Complementary Foods on the Gut Microbiome and Gut Inflammation in Kenyan Infants

Tanja Jaeggi, Guus Kortman, Diego Moretti, Christophe Chassard, Penny Holding, Alexandra Dostal, Jos Boekhorst, Harro Timmerman, Dorine Swinkels, Harold Tjalsma, Jane Njenga, Alice Mwangi, Jane Kvalsvig, Christophe Lacroix & Michael Zimmermann · European Journal of Nutrition & Food Safety · 2015

Objectives: Primary outcome was change in composition of gut microbiome, after 3 weeks and 4 months. Secondary outcomes were changes in faecal calprotectin, treated diarrhoea, anaemia, iron status and systemic inflammation. Methods: We performed two randomized controlled trials i...

Open access Research Article 10.9734/EJNFS/2015/20875